Common mechanisms of auditory hallucinations-perfusion studies in epilepsy

被引:16
作者
Hauf, Martinus [1 ,2 ]
Wiest, Roland [1 ,2 ]
Schindler, Kaspar [2 ,3 ]
Jann, Kay [2 ]
Dierks, Thomas [2 ]
Strik, Werner [2 ]
Schroth, Gerhard [1 ,2 ]
Hubl, Daniela [2 ]
机构
[1] Univ Hosp Bern, Inst Diagnost & Intervent Neuroradiol, Inselspital, Bern, Switzerland
[2] Univ Bern, CH-3012 Bern, Switzerland
[3] Univ Hosp Bern, Div EEG & Epileptol, Dept Neurol, Inselspital, Bern, Switzerland
基金
瑞士国家科学基金会;
关键词
Auditory hallucinations; Primary auditory cortex; Temporal lobe epilepsy; SEIZURES; BRAIN;
D O I
10.1016/j.pscychresns.2012.06.007
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Auditory hallucinations (AH) occur in various neurological and psychiatric disorders. In psychosis, increased neuronal activity in the primary auditory cortex (PAC) contributes to AM. We investigated functional neuroanatomy of epileptic hallucinations by measuring cerebral perfusion in three patients with AH during simple partial status epilepticus. Hyperperfusion in the temporal lobe covering the PAC occurred in all patients. Our perfusion data support the hypothesis of PAC being a constituting element in the genesis of AM independent of their aetiology. (C) 2012 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:268 / 270
页数:3
相关论文
共 15 条
[1]   The hallucinating brain: A review of structural and functional neuroimaging studies of hallucinations [J].
Allen, Paul ;
Laroi, Frank ;
McGuire, Philip K. ;
Aleman, Andre .
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 2008, 32 (01) :175-191
[2]   Activation of Heschl's Gyrus during auditory hallucinations [J].
Dierks, T ;
Linden, DEJ ;
Jandl, M ;
Formisano, E ;
Goebel, R ;
Lanfermann, H ;
Singer, W .
NEURON, 1999, 22 (03) :615-621
[3]   Delusions, illusions and hallucinations in epilepsy: 1. Elementary phenomena [J].
Elliott, Brent ;
Joyce, Eileen ;
Shorvon, Simon .
EPILEPSY RESEARCH, 2009, 85 (2-3) :162-171
[4]   Musical hallucinations [J].
Evers S. .
Current Psychiatry Reports, 2006, 8 (3) :205-210
[5]   Lateralizing value of the auditory aura in partial seizures [J].
Florindo, Irene ;
Bisulli, Francesca ;
Pittau, Francesca ;
Naldi, Ilaria ;
Striano, Pasquale ;
Striano, Salvatore ;
Michelucci, Roberto ;
Testoni, Stefania ;
Baruzzi, Agostino ;
Tinuper, Paolo .
EPILEPSIA, 2006, 47 :68-72
[6]   Cortical Regional Hyperperfusion in Nonconvulsive Status Epilepticus Measured by Dynamic Brain Perfusion CT [J].
Hauf, M. ;
Slotboom, J. ;
Nirkko, A. ;
von Bredow, F. ;
Ozdoba, C. ;
Wiest, R. .
AMERICAN JOURNAL OF NEURORADIOLOGY, 2009, 30 (04) :693-698
[7]   Muting the Voice: A Case of Arterial Spin Labeling-Monitored Transcranial Direct Current Stimulation Treatment of Auditory Verbal Hallucinations [J].
Homan, Philipp ;
Kindler, Jochen ;
Federspiel, Andrea ;
Flury, Richard ;
Hubl, Daniela ;
Hauf, Martinus ;
Dierks, Thomas .
AMERICAN JOURNAL OF PSYCHIATRY, 2011, 168 (08) :853-854
[8]   Hearing dysphasic voices [J].
Hubl, Daniela ;
Hauf, Martinus ;
van Swam, Claudia ;
Mueri, Rene ;
Dierks, Thomas ;
Strik, Werner .
LANCET, 2007, 370 (9586) :538-538
[9]   Competition for neuronal resources: how hallucinations make themselves heard [J].
Hubl, Daniela ;
Koenig, Thomas ;
Strik, Werner K. ;
Garcia, Lester Melie ;
Dierks, Thomas .
BRITISH JOURNAL OF PSYCHIATRY, 2007, 190 :57-62
[10]   An fMRI study of auditory hallucinations in patients with epilepsy [J].
Korsnes, Maria Stylianou ;
Hugdahl, Kenneth ;
Nygard, Merethe ;
Bjornaes, Helge .
EPILEPSIA, 2010, 51 (04) :610-617