Gamma-glutamyl carboxylase (GGCX) microsatellite and warfarin dosing

被引：35
作者：
Chen, LY [1 ]
Eriksson, N [1 ]
Gwilliam, R [1 ]
Bentley, D [1 ]
Deloukas, P [1 ]
Wadelius, M [1 ]
机构：
[1] Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England
来源：
BLOOD | 2005年 / 106卷 / 10期
关键词：
D O I：
10.1182/blood-2005-04-1711
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：3673 / 3674
页数：2
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共 10 条
  • [1] MECHANISM OF ACTION OF WARFARIN - WARFARIN AND METABOLISM OF VITAMIN-K
    BELL, RG
    MATSCHINER, JT
    SADOWSKI, JA
    [J]. BIOCHEMISTRY, 1972, 11 (10) : 1959 - +
  • [2] The vitamin K-dependent carboxylase
    Berkner, KL
    [J]. JOURNAL OF NUTRITION, 2000, 130 (08) : 1877 - 1880
  • [3] ANTICOAGULANT-RELATED BLEEDING - CLINICAL EPIDEMIOLOGY, PREDICTION, AND PREVENTION
    LANDEFELD, CS
    BEYTH, RJ
    [J]. AMERICAN JOURNAL OF MEDICINE, 1993, 95 (03) : 315 - 328
  • [4] Identification of the gene for vitamin K epoxide reductase
    Li, T
    Chang, CY
    Jin, DY
    Lin, PJ
    Khvorova, A
    Stafford, DW
    [J]. NATURE, 2004, 427 (6974) : 541 - 544
  • [5] Compound heterozygous mutations in the γ-glutamyl carboxylase gene cause combined deficiency of all vitamin K-dependent blood coagulation factors
    Rost, S
    Fregin, A
    Koch, D
    Compes, M
    Müller, CR
    Oldenburg, J
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 2004, 126 (04) : 546 - 549
  • [6] Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2
    Rost, S
    Fregin, A
    Ivaskevicius, V
    Conzelmann, E
    Hörtnagel, K
    Pelz, HJ
    Lappegard, K
    Seifried, E
    Scharrer, I
    Tuddenham, EGD
    Müller, CR
    Strom, TM
    Oldenburg, J
    [J]. NATURE, 2004, 427 (6974) : 537 - 541
  • [7] Association of pharmacokinetic (CYP2C9) and pharmacodynamic (factors II, VII, IX, and X; proteins S and C; and γ-glutamyl carboxylase) gene variants with warfarin sensitivity
    Shikata, E
    Ieiri, I
    Ishiguro, S
    Aono, H
    Inoue, K
    Koide, T
    Ohgi, S
    Otsubo, K
    [J]. BLOOD, 2004, 103 (07) : 2630 - 2635
  • [8] Common VKORC1 and GGCX polymorphisms associated with warfarin dose
    Wadelius, M
    Chen, LY
    Downes, K
    Ghori, J
    Hunt, S
    Eriksson, N
    Wallerman, O
    Melhus, H
    Wadelius, C
    Bentley, D
    Deloukas, P
    [J]. PHARMACOGENOMICS JOURNAL, 2005, 5 (04) : 262 - 270
  • [9] Warfarin sensitivity related to CYP2C9, CYP3A5, ABCB1 (MDR1) and other factors
    Wadelius, M
    Sörlin, K
    Wallerman, O
    Karlsson, J
    Yue, QY
    Magnusson, PKE
    Wadelius, C
    Melhus, H
    [J]. PHARMACOGENOMICS JOURNAL, 2004, 4 (01) : 40 - 48
  • [10] Genomic sequence and transcription start site for the human gamma-glutamyl carboxylase
    Wu, SM
    Stafford, DW
    Frazier, LD
    Fu, YY
    High, KA
    Chu, K
    SanchezVega, B
    Solera, J
    [J]. BLOOD, 1997, 89 (11) : 4058 - 4062
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