Notch Signaling

被引：195

作者：

Kopan, Raphael ^{[1
,2
]}

机构：

[1] Washington Univ, Dept Dev Biol, St Louis, MO 63110 USA

[2] Washington Univ, Dept Med, Div Dermatol, St Louis, MO 63110 USA

来源：

COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY | 2012年 / 4卷 / 10期

关键词：

SQUAMOUS-CELL CARCINOMA; DROSOPHILA; MUTATIONS; CLEAVAGE; VPS25; HEAD;

D O I：

10.1101/cshperspect.a011213

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

[No abstract available]

引用

页数：4

共 21 条

[1] Exome Sequencing of Head and Neck Squamous Cell Carcinoma Reveals Inactivating Mutations in NOTCH1 [J].

Agrawal, Nishant ;

Frederick, Mitchell J. ;

Pickering, Curtis R. ;

Bettegowda, Chetan ;

Chang, Kyle ;

Li, Ryan J. ;

Fakhry, Carole ;

Xie, Tong-Xin ;

Zhang, Jiexin ;

Wang, Jing ;

Zhang, Nianxiang ;

El-Naggar, Adel K. ;

Jasser, Samar A. ;

Weinstein, John N. ;

Trevino, Lisa ;

Drummond, Jennifer A. ;

Muzny, Donna M. ;

Wu, Yuanqing ;

Wood, Laura D. ;

Hruban, Ralph H. ;

Westra, William H. ;

Koch, Wayne M. ;

Califano, Joseph A. ;

Gibbs, Richard A. ;

Sidransky, David ;

Vogelstein, Bert ;

Velculescu, Victor E. ;

Papadopoulos, Nickolas ;

Wheeler, David A. ;

Kinzler, Kenneth W. ;

Myers, Jeffrey N. .

SCIENCE, 2011, 333 (6046) :1154-1157

[2] Selective Use of ADAM10 and ADAM17 in Activation of Notch1 Signaling [J].

Bozkulak, Esra Cagavi ;

Weinmaster, Gerry .

MOLECULAR AND CELLULAR BIOLOGY, 2009, 29 (21) :5679-5695

[3] Notch-deficient skin induces a lethal systemic B-lymphoproliferative disorder by secreting TSLP, a sentinel for epidermal integrity [J].

Demehri, Shadmehr ;

Liu, Zhenyi ;

Lee, Jonghyeob ;

Lin, Meei-Hua ;

Crosby, Seth D. ;

Roberts, Christopher J. ;

Grigsby, Perry W. ;

Miner, Jeffrey H. ;

Farr, Andrew G. ;

Kopan, Raphael .

PLOS BIOLOGY, 2008, 6 (05) :992-1005

[4] Effects of S1 Cleavage on the Structure, Surface Export, and Signaling Activity of Human Notch1 and Notch2 [J].

Gordon, Wendy R. ;

Vardar-Ulu, Didem ;

L'Heureux, Sarah ;

Ashworth, Todd ;

Malecki, Michael J. ;

Sanchez-Irizarry, Cheryll ;

McArthur, Debbie G. ;

Histen, Gavin ;

Mitchell, Jennifer L. ;

Aster, Jon C. ;

Blacklow, Stephen C. .

PLOS ONE, 2009, 4 (08)

[5] OSM-11 facilitates LIN-12 Notch signaling during Caenorhabditis elegans vulval development [J].

Komatsu, Hidetoshi ;

Chao, Michael Y. ;

Larkins-Ford, Jonah ;

Corkins, Mark E. ;

Somers, Gerard A. ;

Tucey, Tim ;

Dionne, Heather M. ;

White, Jamie Q. ;

Wani, Khursheed ;

Boxem, Mike ;

Hart, Anne C. .

PLOS BIOLOGY, 2008, 6 (08) :1730-1745

[6] The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism [J].

Kopan, Raphael ;

Ilagan, Ma. Xenia G. .

CELL, 2009, 137 (02) :216-233

[7] The Notch1 receptor is cleaved constitutively by a furin-like convertase [J].

Logeat, F ;

Bessia, C ;

Brou, C ;

LeBail, O ;

Jarriault, S ;

Seidah, NG ;

Israël, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (14) :8108-8112

[8] Antiparallel segregation of notch components in the immunological synapse directs reciprocal signaling in allogeneic Th:DC conjugates [J].

Luty, Winifred H. ;

Rodeberg, David ;

Parness, Jerome ;

Vyas, Yatin M. .

JOURNAL OF IMMUNOLOGY, 2007, 179 (02) :819-829

[9] Mutations in erupted, the Drosophila ortholog of mammalian tumor susceptibility gene 101, elicit non-cell-autonomous overgrowth [J].

Moberg, KH ;

Schelble, S ;

Burdick, SK ;

Hariharan, IK .

DEVELOPMENTAL CELL, 2005, 9 (05) :699-710

[10] Interaction Between Notch and Hif-α in Development and Survival of Drosophila Blood Cells [J].

Mukherjee, Tina ;

Kim, William Sang ;

Mandal, Lolitika ;

Banerjee, Utpal .

SCIENCE, 2011, 332 (6034) :1210-1213

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