Enumeration of cytomegalovirus-specific interferonγ CD8+ and CD4+ T cells early after allogeneic stem cell transplantation may identify patients at risk of active cytomegalovirus infection

被引:45
|
作者
Solano, Carlos [2 ,3 ]
Benet, Isana [2 ]
Clari, Maria A. [1 ]
Nieto, Jose [4 ]
de la Camara, Rafael [5 ]
Lopez, Javier [6 ]
Hernandez-Boluda, Juan C. [2 ]
Remigia, Maria J. [2 ]
Jarque, Isidro [7 ]
Calabuig, Maria L. [2 ]
Garcia-Noblejas, Ana [5 ]
Alberola, Juan [8 ]
Tamarit, Amparo [8 ]
Gimeno, Concepcion [1 ,8 ]
Navarro, David [1 ,8 ]
机构
[1] Hosp Clin Univ, Microbiol Serv, Valencia, Spain
[2] Hosp Clin Univ, Hematol & Med Oncol Serv, Valencia, Spain
[3] Univ Valencia, Sch Med, Dept Med, E-46003 Valencia, Spain
[4] Hosp Morales Meseguer, Hematol Serv, Murcia, Spain
[5] Hosp La Princesa, Hematol Serv, Madrid, Spain
[6] Hosp Ramon & Cajal, Hematol Serv, E-28034 Madrid, Spain
[7] Hosp Univ La Fe, Hematol Serv, Valencia, Spain
[8] Univ Valencia, Sch Med, Dept Microbiol, Valencia, Spain
来源
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL | 2008年 / 93卷 / 09期
关键词
D O I
10.3324/haematol.12880
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1434 / 1436
页数:3
相关论文
共 50 条
  • [21] Protective Immunity Transferred by Infusion of Cytomegalovirus-Specific CD8+ T Cells within Donor Grafts: Its Associations with Cytomegalovirus Reactivation Following Unmanipulated Allogeneic Hematopoietic Stem Cell Transplantation
    Luo, Xiao-Hua
    Huang, Xiao-Jun
    Liu, Kai-Yan
    Xu, Lan-Ping
    Liu, Dai-Hong
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2010, 16 (07) : 994 - 1004
  • [22] Tetramer-based quantification of cytomegalovirus (CMV)-specific CD8+ T lymphocytes in T-cell-depleted stem cell grafts and after transplantation may identify patients at risk for progressive CMV infection
    Gratama, JW
    van Esser, JWJ
    Lamers, CHJ
    Toumay, C
    Löwenberg, B
    Bolhuis, RLH
    Cornelissen, JJ
    BLOOD, 2001, 98 (05) : 1358 - 1364
  • [23] Adoptive transfer and selective reconstitution of streptamer-selected cytomegalovirus-specific CD8+ T cells leads to virus clearance in patients after allogeneic peripheral blood stem cell transplantation
    Schmitt, Anita
    Tonn, Torsten
    Busch, Dirk H.
    Grigoleit, Goetz Ulrich
    Einsele, Hermann
    Odendahl, Marcus
    Germeroth, Lothar
    Ringhoffer, Mark
    Ringhoffer, Simone
    Wiesneth, Markus
    Greiner, Jochen
    Michel, Detlef
    Mertens, Thomas
    Rojewski, Markus
    Marx, Martin
    von Harsdorf, Stephanie
    Doehner, Hartmut
    Seifried, Erhard
    Bunjes, Donald
    Schmitt, Michael
    TRANSFUSION, 2011, 51 (03) : 591 - 599
  • [24] Direct visualisation of cytomegalovirus-specific CD8+ T cells in renal transplant recipients
    Hilton, RM
    Hargreaves, REG
    Sacks, SH
    O'Callaghan, CA
    TRANSPLANTATION PROCEEDINGS, 2002, 34 (04) : 1171 - 1173
  • [25] Differentiation of cytomegalovirus-specific CD8+ T cells in healthy and immunosuppressed virus carriers
    Gamadia, LE
    Rentenaar, RJ
    Baars, PA
    Remmerswaal, EBM
    Surachno, S
    Weel, JFL
    Toebes, M
    Schumacher, TNM
    ten Berge, IJM
    van Lier, RAW
    BLOOD, 2001, 98 (03) : 754 - 761
  • [26] Diverse Specificities, Phenotypes, and Antiviral Activities of Cytomegalovirus-Specific CD8+ T Cells
    Jackson, S. E.
    Mason, G. M.
    Okecha, G.
    Sissons, J. G. P.
    Wills, M. R.
    JOURNAL OF VIROLOGY, 2014, 88 (18) : 10894 - 10908
  • [27] Cytomegalovirus reactivation following allogeneic stem cell transplantation is associated with the presence of dysfunctional antigen-specific CD8+ T cells
    Özdemir, E
    St John, LS
    Gillespie, G
    Rowland-Jones, S
    Champlin, RE
    Molldrem, JJ
    Komanduri, KV
    BLOOD, 2002, 100 (10) : 3690 - 3697
  • [28] Adoptive transfer of cytomegalovirus-specific CD8+T-cells powered by streptamer technology leads to enduring virus clearance in patients after allogeneic stem cell transplantation
    Schmitt, A.
    Tonn, T.
    Busch, D.
    Grigoleit, G.
    Einsele, H.
    Odenthal, M.
    Germeroth, L.
    Ringhoffer, M.
    Ringhoffer, S.
    Wiesneth, M.
    Michel, D.
    Mertens, T.
    Rojewski, M.
    Marx, M.
    von Harsdorf, S.
    Doehner, H.
    Seifried, E.
    Bunjes, D.
    Schmitt, M.
    BONE MARROW TRANSPLANTATION, 2009, 43 : S246 - S246
  • [29] Adoptive Therapy with Cytomegalovirus-Specific Cytotoxic T Lymphocytes for Refractory Cytomegalovirus Infection and Disease after Allogeneic Hematopoietic Stem Cell Transplantation
    Jiang, Zhonghui
    Fan, Zhiping
    Xu, Hui
    Xu, Na
    Zhang, Tian
    Xue, Huiwen
    Lin, Ren
    Wang, Zhixiang
    Jiang, Ling
    Sun, Jing
    Xuan, Li
    BLOOD, 2023, 142
  • [30] CD4+ BUT NOT CD8+ T CELLS ARE REQUIRED FOR PROTECTION AGAINST SEVERE GUINEA PIG CYTOMEGALOVIRUS INFECTION
    Rollman, Tyler
    Berkebile, Zachary
    Hatfield, Jason
    Hicks, Dustin
    Pravetoni, Marco
    Milligan, Gregg
    Schleiss, Mark
    Morgan, Terry
    Bierle, Craig
    PLACENTA, 2023, 140 : E21 - E21