Simulation of the mechanism of liquid stationary phase retention in a rotating coiled column: Hydrophilic liquid systems

被引：3
作者：
Fedotov, PS [1 ]
Kronrod, VA [1 ]
Maryutina, TA [1 ]
Spivakov, BY [1 ]
机构：
[1] Russian Acad Sci, Vernadsky Inst Geochem & Analyt chem, Moscow 119991, Russia
来源：
JOURNAL OF ANALYTICAL CHEMISTRY | 2002年 / 57卷 / 02期
基金：
俄罗斯基础研究基金会;
关键词：
D O I：
10.1023/A:1014003621155
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A mathematical model was developed which describes the behavior of various liquid systems in a rotating coiled column used in countercurrent chromatography. The conditions of retaining the liquid stationary phase were described in detail for hydrophilic (slowly settling) systems. Various forces that act on liquids in the column were considered. Equations were derived for the steady-state retention process. Mathematical expressions were obtained which make it possible to estimate the stationary-phase volume retained in a column with consideration for the physicochemical properties of the liquid system in use, the speed of column rotation, and the main design parameters of the planet centrifuge. This volume directly affects the column capacity and separation efficiency, and it is crucial for choosing liquid systems and experimental conditions.
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收藏
页码：145 / 149
页数：5
相关论文
共 6 条
[1]  
FEDOTOV PS, 2002, ZH ANAL KHIM, V57, P30
[2]   EXPERIMENTAL-OBSERVATIONS OF THE HYDRODYNAMIC BEHAVIOR OF SOLVENT SYSTEMS IN HIGH-SPEED COUNTERCURRENT CHROMATOGRAPHY .2. PHASE DISTRIBUTION DIAGRAMS FOR HELICAL AND SPIRAL COLUMNS [J].
ITO, Y .
JOURNAL OF CHROMATOGRAPHY, 1984, 301 (02) :387-403
[3]  
Mandava N.B., 1988, COUNTER CURRENT CHRO, V44, P79
[4]   CLASSIFICATION OF COUNTERCURRENT CHROMATOGRAPHY SOLVENT SYSTEMS ON THE BASIS OF THE CAPILLARY WAVELENGTH [J].
MENET, JM ;
THIEBAUT, D ;
ROSSET, R ;
WESFREID, JE ;
MARTIN, M .
ANALYTICAL CHEMISTRY, 1994, 66 (01) :168-176
[5]  
PEYRET R, 1984, COMPUTATIONAL METHOD
[6]  
Tikhonov AN., 1977, Equation of Mathematical Physics
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