Stroke and Obstructive Sleep Apnea: A Review

被引：30
作者：
Barone, Daniel A. [1 ]
Krieger, Ana C. [1 ,2 ,3 ]
机构：
[1] Cornell Univ, Weill Cornell Med Coll, Ctr Sleep Med, Dept Neurol, New York, NY 10065 USA
[2] Cornell Univ, Weill Cornell Med Coll, Ctr Sleep Med, Dept Med, New York, NY 10065 USA
[3] Cornell Univ, Weill Cornell Med Coll, Ctr Sleep Med, Dept Med Genet, New York, NY 10065 USA
来源：
CURRENT ATHEROSCLEROSIS REPORTS | 2013年 / 15卷 / 07期
关键词：
Stroke; Sleep apnea; Obstructive sleep apnea; Thrombosis; Cardiovascular disease; Cerebrovascular disease; POSITIVE AIRWAY PRESSURE; RISK-FACTOR; ISCHEMIC-STROKE; ATRIAL-FIBRILLATION; CEREBRAL AUTOREGULATION; CARDIOVASCULAR-DISEASE; MYOCARDIAL-INFARCTION; INTERMITTENT HYPOXIA; BREATHING DISORDERS; INSULIN-RESISTANCE;
D O I：
10.1007/s11883-013-0334-8
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
Obstructive sleep apnea (OSA) has been found to be an independent risk factor for stroke in large epidemiological studies. The mechanisms underlying this relationship have been investigated over the past 2-3 decades, with a particular focus on identifying pathophysiological pathways and risk modification strategies. Despite the advancements made, the specific understanding of the implicated mechanisms is still limited. This brief review focuses on presenting some of the epidemiological evidence of the linkage between OSA and stroke, discussing mechanistic pathways and the potential effect of OSA treatment in modulating the risk for stroke in these patients. Future directions for research in this field are also discussed.
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页数：7
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