CRISPR/Cas9-edited NSG mice as PDX models of human leukemia to address the role of niche-derived SPARC

被引：7
作者：
Tirado-Gonzalez, I. [1 ]
Czlonka, E. [1 ]
Nevmerzhitskaya, A. [1 ]
Soetopo, D. [1 ]
Bergonzani, E. [1 ]
Mahmoud, A. [1 ]
Contreras, A. [1 ]
Jeremias, I. [2 ,3 ]
Platzbecker, U. [3 ,4 ]
Bourquin, J. P. [5 ]
Kloz, U. [5 ]
Van der Hoeven, F. [6 ]
Medyouf, H. [1 ,7 ,8 ]
机构：
[1] Georg Speyer Haus, Inst Tumor Biol & Expt Therapy, Frankfurt, Germany
[2] Helmholtz Ctr Munich, Dept Apoptosis Hematopoiet Stem Cells, German Ctr Environm Hlth HMGU, Munich, Germany
[3] German Canc Consortium, DKTK Partner Site Munich, Heidelberg, Germany
[4] Tech Univ Dresden, Univ Hosp Carl Gustav Carus, Dresden, Germany
[5] Univ Childrens Hosp, Div Pediat Oncol, Zurich, Switzerland
[6] German Canc Res Ctr, Transgen Serv, Heidelberg, Germany
[7] German Canc Consortium, DKTK Partner Site Frankfurt Mainz, Heidelberg, Germany
[8] Heidelberg Univ, Univ Hosp Mannheim, Med Fac, Dept Hematol & Oncol, Mannheim, Germany
来源：
LEUKEMIA | 2018年 / 32卷 / 04期
基金：
欧洲研究理事会;
关键词：
ACUTE MYELOID-LEUKEMIA; ENGRAFTMENT; PREDICTS; GROWTH;
D O I：
10.1038/leu.2017.346
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：1048 / 1051
页数：4
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