SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF NEW SERIES OF 2-PHENYL-3-[2-(5-SUBSTITUTED-1,3,4-OXADIAZOL-2-YL) ETHYL]-1H-INDOLES

被引：0

作者：

Purohit, Shriram S. ^{[1
]}

Kamlesh, Ghori ^{[1
]}

Kumar, Devendra ^{[1
]}

机构：

[1] SETs Coll Pharm, Dept Pharmaceut Chem, Dharwad 580002, Karnataka, India

来源：

INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2013年 / 23卷 / 02期

关键词：

SUBSTITUTED 1,3,4-OXADIAZOLE; DERIVATIVES; ANTICONVULSANT; ANTIBACTERIAL;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

This research article presents the synthesis and antimicrobial activity of a new series of 2-phenyl-3-[2-(5-substituted-1,3,4-oxadiazol-2-yl) ethyl]-1H-indoles 5(a-f). The structures of the compounds were confirmed by FT-IR, H-1 NMR and Mass spectral data. All the derivatives have shown moderate to excellent antimicrobial activities. 5a has shown remarkable Minimum Inhibitory Concentration especially against Bacillus subtilis, Klebsiella pneumoniae, Candida albicans, Aspergillus niger when compared with the standard drugs.

引用

页码：177 / 182

页数：6

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