Cytokinesis: mind the GAP

被引：11

作者：

D'Avino, Pier Paolo ^{[1
]}

Glover, David M. ^{[2
]}

机构：

[1] Univ Cambridge, Dept Pathol, Cambridge CB2 1QP, England

[2] Univ Cambridge, Dept Genet, Canc Res UK Cell Cycle Genet Res Grp, Cambridge CB2 3EH, England

来源：

NATURE CELL BIOLOGY | 2009年 / 11卷 / 02期

关键词：

GTPASE-ACTIVATING PROTEIN; CONTRACTILE RING; MGCRACGAP; RHO; SPINDLE; COMPLEX; CENTRALSPINDLIN; RAC;

D O I：

10.1038/ncb0209-112

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Cytokinesis ensures proper partitioning of genomic and cytoplasmic material between dividing cells. a key regulator of this process is the centralspindlin complex. Two recent papers report that GAP activity of one of the members of this complex regulates the function of Rho family GTPases during cytokinesis.

引用

页码：112 / 114

页数：3

共 16 条

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