A Physical Model of Blood Platelets Shape and its Effect on Light Scattering

被引:0
作者
Moskalensky, Alexander E. [1 ,2 ]
Litvinenko, Alyona L. [1 ,2 ]
Nekrasov, Vyacheslav M. [1 ,2 ]
Yurkin, Maxim A. [1 ,2 ]
机构
[1] Novosibirsk State Univ, Novosibirsk 630090, Russia
[2] Voevodsky Inst Chem Kinet & Combust, Novosibirsk, Russia
来源
2016 URSI INTERNATIONAL SYMPOSIUM ON ELECTROMAGNETIC THEORY (EMTS) | 2016年
关键词
MARGINAL BAND; AGGREGATION; MICROTUBULE; ACTIVATION;
D O I
暂无
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Quantitative description of blood platelet shape and its dramatic change during activation is necessary for the correct interpretation of light-scattering data, routinely measured in diagnostic laboratories. We propose the model of platelet shape, based on the known information on the cell cytoskeleton. The model geometry is characterized by two parameters: the cell volume and the overcurvature of the internal microtubule bundle, which changes during platelet activation. We describe the procedure for the construction of a cell shape given the volume and overcurvature, and also the way for simulation of light scattering by such objects.
引用
收藏
页码:583 / 585
页数:3
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