Fungal keratitis caused by Podospora austroamericana: A first case report

被引:0
作者
Rameshkumar, Gunasekaran [1 ]
Ponlakshmi, Mariappan [1 ]
Selvapandiyan, Appavu [1 ]
Ramsudharsan, Ravindran [2 ]
Krishnan, Raja Subramanian [3 ]
Lalitha, Prajna [1 ]
机构
[1] Aravind Eye Hosp & Post Grad Inst Ophthalmol, Dept Ocular Microbiol, 1 Anna Nagar, Madurai 625020, Tamil Nadu, India
[2] Aravind Eye Hosp & Post Grad Inst Ophthalmol, Dept Intraocular Lens & Cataract Serv, Madurai, Tamil Nadu, India
[3] Aravind Eye Hosp & Post Grad Inst Ophthalmol, Dept Cornea & Refract Surg Serv, Madurai, Tamil Nadu, India
关键词
DNA sequencing; keratitis; panophthalmitis; polymerase chain reaction; REVISION;
D O I
10.4103/ijmm.IJMM_19_1
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We report a case of keratitis caused by a rare fungus Podospora austroamericana. Clinical and microbiological evaluation of the corneal ulcer was done and the treatment outcome was studied. The fungus was grown from the corneal scraping, and it was identified as P. austroamericana based on DNA sequence and analysis of the internal transcribed spacer region. The patient was treated with topical azithromycin, natamycin and voriconazole. Despite maximum medical therapy, the ulcer progressed very rapidly and the patient developed panophthalmitis and evisceration of the eye had to be done. This is the first reported case of keratitis caused by P. austroamericana.
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页码:594 / 596
页数:3
相关论文
共 9 条
[1]  
Cai L, 2005, FUNGAL DIVERS, V19, P1
[2]  
Clinical and Laboratory Standards Institute, 2008, M38A2 CLSI
[3]   Rapid detection and identification of Candida, Aspergillus, and Fusarium species in ocular samples using nested PCR [J].
Jaeger, EEM ;
Carroll, NM ;
Choudhury, S ;
Dunlop, AAS ;
Towler, HMA ;
Matheson, MM ;
Adamson, P ;
Okhravi, N ;
Lightman, S .
JOURNAL OF CLINICAL MICROBIOLOGY, 2000, 38 (08) :2902-2908
[4]   Trends in bacterial and fungal keratitis in South India, 2002-2012 [J].
Lalitha, Prajna ;
Prajna, Namperumalsamy V. ;
Manoharan, Geetha ;
Srinivasan, Muthiah ;
Mascarenhas, Jeena ;
Das, Manoranjan ;
D'Silva, Sean S. ;
Porco, Travis C. ;
Keenan, Jeremy D. .
BRITISH JOURNAL OF OPHTHALMOLOGY, 2015, 99 (02) :192-194
[5]  
LUNDQVIST N, 1972, SYMB BOT UPSAL, V20, P1
[6]   REVISION OF GENUS PODOSPORA [J].
MIRZA, JH ;
CAIN, RF .
CANADIAN JOURNAL OF BOTANY, 1969, 47 (12) :1999-&
[7]  
Saha Suman, 2009, Oman J Ophthalmol, V2, P114, DOI 10.4103/0974-620X.57310
[8]   Comparative study on the incidence and outcomes of pigmented versus non pigmented keratomycosis [J].
Sengupta, Sabyasachi ;
Rajan, Sanjeevani ;
Reddy, Padmati Ravindranath ;
Thiruvengadakrishnan, Krishnan ;
Ravindran, Ravilla D. ;
Lalitha, Prajna ;
Vaitilingam, C. Manivasagam .
INDIAN JOURNAL OF OPHTHALMOLOGY, 2011, 59 (04) :291-296
[9]   A new species of Podospora from soil in Chile [J].
Stchigel, AM ;
Calduch, M ;
Guarro, J .
MYCOLOGIA, 2002, 94 (03) :554-558