Detection of floccular hypometabolism in downbeat nystagmus by fMRI

被引：65

作者：

Kalla, R ^{[1
]}

Deutschlander, A ^{[1
]}

Hufner, K ^{[1
]}

Stephan, T ^{[1
]}

Jahn, K ^{[1
]}

Glasauer, S ^{[1
]}

Brandt, T ^{[1
]}

Strupp, M ^{[1
]}

机构：

[1] Univ Munich, Dept Neurol, D-8000 Munich, Germany

来源：

NEUROLOGY | 2006年 / 66卷 / 02期

关键词：

D O I：

10.1212/01.wnl.0000194242.28018.d9

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors evaluated floccular activity with fMRI during the performance of vertical smooth pursuit eye movements in four patients with downbeat nystagmus (DBN) due to cerebellar degeneration and in 16 healthy controls. Region of interest analysis revealed a significantly diminished activation of both floccular lobes during downward but not upward pursuit in DBN. These imaging data support the view that a functional deficiency of the flocculi in downward pursuit causes DBN.

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收藏

页码：281 / 283

页数：3

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