Serological markers in inflammatory bowel disease: the pros and cons

被引：6

作者：

Lerner, A ^{[1
]}

Shoenfeld, Y ^{[1
]}

机构：

[1] Technion Israel Inst Technol, B Rappaport Sch Med, Carmel Med Ctr, Dept Paediat,Paediat Gastroenterol & Nutr Unit, Haifa, Israel

来源：

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY | 2002年 / 14卷 / 02期

关键词：

anti-Saccharomyces cerevisiae mannan antibodies; Crohn's disease; inflammatory bowel disease; perinuclear antineutrophil cytoplasmic autoantibodies; ulcerative colitis;

D O I：

10.1097/00042737-200202000-00002

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Accurate serological assays are desirable for the diagnosis of inflammatory bowel disease. Among several serological markers anti-Saccharomyces cerevisiae mannan antibodies and perinuclear antineutrophil cytoplasmic autoantibodies are highly disease specific for Crohn's disease and ulcerative colitis, respectively. Combining the two improves their specificity. Sensitivity, however, is still low. Due to lack of standardization and vast interobserver variability, they cannot be used as the only diagnostic criteria but can assist clinicians in diagnosing and categorizing patients with inflammatory bowel disease as well as in helping them to take therapeutic decisions. Eur J Gastroenterol Hepatol 14:103-105 (C) 2002 Lippincott Williams Wilkins.

引用

页码：103 / 105

页数：3

共 17 条

[1] THE EFFECT OF DIETARY YEAST ON THE ACTIVITY OF STABLE CHRONIC CROHNS-DISEASE [J].