Simple and Efficient One-Pot Synthesis of 2-Substituted Benzimidazoles from -Diaminoarene and Aryl Aldehydes

被引:18
|
作者
Alapati, Mohan Lakshmi Punna Rao [1 ,2 ]
Abburi, Sridhar Rao [1 ,2 ]
Mukkamala, Saratchandra Babu [1 ]
Rao, M. Krishnaji [2 ]
机构
[1] GITAM Univ, GITAM Inst Sci, Dept Chem, Visakhapatnam 530045, Andhra Pradesh, India
[2] DIVIS Labs Ltd, Unit 2, Qual Control Dept, Visakhapatnam, Andhra Pradesh, India
关键词
Aldehydes; benzimidazole; -diaminoarene; iodine; urea hydrogen peroxide; HYDROGEN-PEROXIDE; AROMATIC-ALDEHYDES; CONVENIENT; OXIDATION; AGENTS; 2-ARYLBENZIMIDAZOLES; INHIBITORS; MILD;
D O I
10.1080/00397911.2015.1083581
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An easy and efficient one-pot condensation method for the synthesis of substituted benzimidazoles from -phenylenediamines with aryl aldehydes using urea hydrogen peroxide (UHP) and I-2 in dimethylsulfoxide (DMSO) provides wide substrate scope with good to excellent yields and simple and quick isolation of the products.
引用
收藏
页码:2436 / 2443
页数:8
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