Simple and Efficient One-Pot Synthesis of 2-Substituted Benzimidazoles from -Diaminoarene and Aryl Aldehydes

被引：19

作者：

Alapati, Mohan Lakshmi Punna Rao ^{[1
,2
]}

Abburi, Sridhar Rao ^{[1
,2
]}

Mukkamala, Saratchandra Babu ^{[1
]}

Rao, M. Krishnaji ^{[2
]}

机构：

[1] GITAM Univ, GITAM Inst Sci, Dept Chem, Visakhapatnam 530045, Andhra Pradesh, India

[2] DIVIS Labs Ltd, Unit 2, Qual Control Dept, Visakhapatnam, Andhra Pradesh, India

来源：

SYNTHETIC COMMUNICATIONS | 2015年 / 45卷 / 21期

关键词：

Aldehydes; benzimidazole; -diaminoarene; iodine; urea hydrogen peroxide; HYDROGEN-PEROXIDE; AROMATIC-ALDEHYDES; CONVENIENT; OXIDATION; AGENTS; 2-ARYLBENZIMIDAZOLES; INHIBITORS; MILD;

D O I：

10.1080/00397911.2015.1083581

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An easy and efficient one-pot condensation method for the synthesis of substituted benzimidazoles from -phenylenediamines with aryl aldehydes using urea hydrogen peroxide (UHP) and I-2 in dimethylsulfoxide (DMSO) provides wide substrate scope with good to excellent yields and simple and quick isolation of the products.

引用

页码：2436 / 2443

页数：8

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