A joint analysis of influenza-associated hospitalizations and mortality in Hong Kong, 1998-2013

被引：57

作者：

Wu, Peng ^{[1
]}

Presanis, Anne M. ^{[2
]}

Bond, Helen S. ^{[1
]}

Lau, Eric H. Y. ^{[1
]}

Fang, Vicky J. ^{[1
]}

Cowling, Benjamin J. ^{[1
]}

机构：

[1] Univ Hong Kong, WHO Collaborating Ctr Infect Dis Epidemiol & Cont, Sch Publ Hlth, Li Ka Shing Fac Med, Hong Kong, Peoples R China

[2] Cambridge Inst Publ Hlth, Med Res Council Biostat Unit, Cambridge, England

来源：

SCIENTIFIC REPORTS | 2017年 / 7卷

基金：

英国医学研究理事会;

关键词：

ACUTE MYOCARDIAL-INFARCTION; RESPIRATORY SYNCYTIAL VIRUS; SEASONAL INFLUENZA; EXCESS MORTALITY; UNITED-STATES; INFECTION; RISK; ADULTS; COMPLICATIONS; OUTCOMES;

D O I：

10.1038/s41598-017-01021-x

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Influenza viruses may cause severe human infections leading to hospitalization or death. Linear regression models were fitted to population-based data on hospitalizations and deaths. Surveillance data on influenza virus activity permitted inference on influenza-associated hospitalizations and deaths. The ratios of these estimates were used as a potential indicator of severity. Influenza was associated with 431 (95% CrI: 358-503) respiratory deaths and 12,700 (95% CrI: 11,700-13,700) respiratory hospitalizations per year. Majority of the excess deaths occurred in persons >= 65 y of age. The ratios of deaths to hospitalizations in adults >= 65 y were significantly higher for influenza A(H1N1) and A(H1N1)pdm09 compared to A(H3N2) and B. Substantial disease burden associated with influenza viruses were estimated in Hong Kong particularly among children and elderly in 1998-2013. Infections with influenza A(H1N1) was suggested to be more serious than A(H3N2) in older adults.

引用

页数：7

共 30 条

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