Turn-on selective vitamin B6 derivative fluorescent probe for histidine detection in biological samples

被引:32
|
作者
Oliveira, Elisabete [1 ,2 ]
Santos, Carla [1 ]
Poeta, Patricai [2 ]
Capelo, Jose Luis [1 ]
Lodeiro, Carlos [1 ]
机构
[1] Univ Nova Lisboa, Fac Sci & Technol, Dept Chem, BIOSCOPE Grp,REQUIMTE CQFB, P-2829516 Monte De Caparica, Portugal
[2] Univ Tras os Montes, CECAV, Dept Vet Sci, P-5001801 Alto Douro, Vila Real, Portugal
关键词
ALZHEIMERS-DISEASE; AMINO-ACIDS; NAKED-EYE; SENSORS; ELECTROPHORESIS; CHEMOSENSORS; ENHANCEMENT; RECOGNITION; IMIDAZOLE; ENSEMBLE;
D O I
10.1039/c3an00324h
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A new compound L soluble in water derived from vitamin B6 was successfully synthesized and characterized. The complex LAl3+ is a turn-on selective fluorescent probe for histidine in HEPES buffer, with detection and quantification limits of 0.3 mu M and 0.6 mu M, respectively. The application of the complex LAl3+ in real urine samples is reported.
引用
收藏
页码:3642 / 3645
页数:4
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