Circulating allergen-specific TH2 lymphocytes: CCR4+ rather than CLA+ is the predominant phenotype in peanut-allergic subjects

被引:16
作者
Blom, Lars H. [1 ]
Juel-Berg, Nanna [1 ,2 ]
Larsen, Lau Fabricius [1 ]
Hansen, Kirsten S. [1 ,2 ]
Poulsen, Lars K. [1 ]
机构
[1] Copenhagen Univ Hosp Herlev Gentofte, Dept Dermatol & Allergy, Allergy Clin, Copenhagen, Denmark
[2] Copenhagen Univ Hosp Herlev Gentofte, Dept Pediat, Copenhagen, Denmark
关键词
ATOPIC-DERMATITIS; T-CELLS; RESPONSES; IL-5(+);
D O I
10.1016/j.jaci.2017.10.037
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
[No abstract available]
引用
收藏
页码:1498 / +
页数:9
相关论文
共 12 条
[1]   The immunoglobulin superfamily member CD200R identifies cells involved in type 2 immune responses [J].
Blom, L. H. ;
Martel, B. C. ;
Larsen, L. F. ;
Hansen, C. V. ;
Christensen, M. P. ;
Juel-Berg, N. ;
Litman, T. ;
Poulsen, L. K. .
ALLERGY, 2017, 72 (07) :1081-1090
[2]   In vitro Th1 and Th2 cell polarization is severely influenced by the initial ratio of naive and memory CD4+T cells [J].
Blom, Lars ;
Poulsen, Lars K. .
JOURNAL OF IMMUNOLOGICAL METHODS, 2013, 397 (1-2) :55-60
[3]   IL-9 is a key component of memory TH cell peanut-specific responses from children with peanut allergy [J].
Brough, Helen A. ;
Cousins, David J. ;
Munteanu, Alina ;
Wong, Yuen Fei ;
Sudra, Asha ;
Makinson, Kerry ;
Stephens, Alick C. ;
Arno, Matthew ;
Ciortuz, Liviu ;
Lack, Gideon ;
Turcanu, Victor .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2014, 134 (06) :1329-+
[4]   Cutaneous lymphocyte antigen and α4β7 T-lymphocyte responses are associated with peanut allergy and tolerance in children [J].
Chan, S. M. H. ;
Turcanu, V. ;
Stephens, A. C. ;
Fox, A. T. ;
Grieve, A. P. ;
Lack, G. .
ALLERGY, 2012, 67 (03) :336-342
[5]   Circulating CLA+ T cells in atopic dermatitis and their possible role as peripheral biomarkers [J].
Czarnowicki, T. ;
Santamaria-Babi, L. F. ;
Guttman-Yassky, E. .
ALLERGY, 2017, 72 (03) :366-372
[6]   Ara h 1-reactive T cells in individuals with peanut allergy [J].
DeLong, Jonathan H. ;
Simpson, Kelly Hetherington ;
Wambre, Erik ;
James, Eddie A. ;
Robinson, David ;
Kwok, William W. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2011, 127 (05) :1211-U503
[7]   Mouse CCL8, a CCR8 agonist, promotes atopic dermatitis by recruiting IL-5+ TH2 cells [J].
Islam, Sabina A. ;
Chang, Daniel S. ;
Colvin, Richard A. ;
Byrne, Mike H. ;
McCully, Michelle L. ;
Moser, Bernhard ;
Lira, Sergio A. ;
Charo, Israel F. ;
Luster, Andrew D. .
NATURE IMMUNOLOGY, 2011, 12 (02) :167-U86
[8]   Update on risk factors for food allergy [J].
Lack, Gideon .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2012, 129 (05) :1187-1197
[9]   Lung dendritic cells imprint T cell lung homing and promote lung immunity through the chemokine receptor CCR4 [J].
Mikhak, Zamaneh ;
Strassner, James P. ;
Luster, Andrew D. .
JOURNAL OF EXPERIMENTAL MEDICINE, 2013, 210 (09) :1855-1869
[10]   Hematopoietic prostaglandin D synthase defines a proeosinophilic pathogenic effector human TH2 cell subpopulation with enhanced function [J].
Mitson-Salazar, Alyssa ;
Yin, Yuzhi ;
Wansley, Daniel L. ;
Young, Michael ;
Bolan, Hyejeong ;
Arceo, Sarah ;
Ho, Nancy ;
Koh, Christopher ;
Milner, Joshua D. ;
Stone, Kelly D. ;
Wank, Stephen A. ;
Prussin, Calman .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2016, 137 (03) :907-+