Association Between Nonalcoholic Fatty Liver Disease and Coronary Artery Disease Complexity in Patients With Acute Coronary Syndrome: A Pilot Study

被引：36
|
作者：
Agac, Mustafa Tarik [1 ]
Korkmaz, Levent [1 ]
Cavusoglu, Goekhan [2 ]
Karadeniz, Ayse Gul [2 ]
Agac, Suret [3 ]
Bektas, Huseyin [1 ]
Erkan, Hakan [1 ]
Varol, Mustafa Oguz [1 ]
Vatan, Mehmet Bulent [4 ]
Acar, Zeydin [1 ]
Mentese, Umit [5 ]
Celik, Sukrue [1 ]
机构：
[1] Ahi Evren Cardiovasc & Thorac Surg Training & Res, Dept Cardiol, TR-61187 Trabzon, Turkey
[2] Ahi Evren Cardiovasc & Thorac Surg Training & Res, Dept Radiol, TR-61187 Trabzon, Turkey
[3] Karadeniz Tech Univ, Dept Biochem, Fac Med, Trabzon, Turkey
[4] Sakarya Univ, Dept Cardiol, Fac Med, Sakarya, Turkey
[5] Ahi Evren Cardiovasc & Thorac Surg Training & Res, Dept Cardiovasc Surg, TR-61187 Trabzon, Turkey
来源：
ANGIOLOGY | 2013年 / 64卷 / 08期
关键词：
nonalcoholic fatty liver disease; SYNTAX score; acute coronary syndrome; INCREASED PREVALENCE; SEVERITY; ATHEROSCLEROSIS;
D O I：
10.1177/0003319713479155
中图分类号：
R6 [外科学];
学科分类号：
1002 ; 100210 ;
摘要：
Nonalcoholic fatty liver disease (NAFLD) is highly prevalent in patients with acute coronary syndrome (ACS). We assessed the association between NAFLD and SYNTAX Score (SS) in patients with ACS. Eighty consecutive patients with ACS were enrolled. Patients were evaluated using ultrasound to detect NAFLD and hepatosteatosis stage. The prevalence of NAFLD was 81.2%; median SS was 15. The SS was significantly higher in patients with NAFLD (18 +/- 8 vs. 11 +/- 5, P = .001). Univariate analysis showed that the stage of NAFLD correlated with SS (r = .6, P < .001). In multivariate binary logistic analysis, increased age (odds ratio [OR], 1.05; 95% confidence interval [CI],1.00-1.10) and presence of NAFLD (OR, 13.20; 95% CI, 2.52-69.15) were independent factors associated with supramedian SS. In conclusion, among patients with ACS, those with NAFLD have more complex CAD as assessed by SS.
引用
收藏
页码：604 / 608
页数：5
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