A Novel Copper-Catalyzed Synthesis of N-Monosubstituted 2-Alkynimi-damides from 1-Alkynes and Trichloroacetamidines

被引：0

作者：

Dastjerdi, Hossein Fasihi ^{[1
]}

Nematpour, Manijeh ^{[2
]}

Rezaee, Elham ^{[2
]}

Jahani, Mehdi ^{[3
]}

Tabatabai, Sayyed Abbas ^{[2
]}

机构：

[1] Shahid Beheshti Univ Med Sci, Dept & Fac Pharm, Student Res Comm, Tehran, Iran

[2] Shahid Beheshti Univ Med Sci, Sch Pharm, Dept Pharmaceut Chem, Tehran, Iran

[3] Sharif Univ Technol, Dept Chem, Tehran, Iran

来源：

LETTERS IN ORGANIC CHEMISTRY | 2020年 / 17卷 / 09期

关键词：

Terminal alkynes; copper iodide; alkynylimidamide; cross-coupling; aniline; one-pot reaction; PROPYNE IMINIUM SALTS; ALKYNYL IMINES; TRICHLOROACETONITRILE; DERIVATIVES;

D O I：

10.2174/1570178616666191023142821

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A one-pot Cu-catalyzed synthesis of functionalized alkynyl imidamide by terminal alkynes, trichloroacetonitrile and aniline or benzyl amine is reported. The compounds were produced via coupling reaction of terminal alkynes with trichloroacetamidine. This method was performed under mild, ligand-free conditions and easy work-up method.

引用

页码：704 / 708

页数：5

共 22 条

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