The synthesis of fluorine-containing pterins

被引：9
|
作者：
Dunn, C [1 ]
Gibson, CL [1 ]
Suckling, CJ [1 ]
机构：
[1] UNIV STRATHCLYDE, DEPT PURE & APPL CHEM, GLASGOW G1 1XL, LANARK, SCOTLAND
来源：
TETRAHEDRON | 1996年 / 52卷 / 40期
关键词：
D O I：
10.1016/0040-4020(96)00782-X
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis of some 7,7-difluoro-7,8-digydropterins and pterins with fluoroalkyl subsitutents at the 6 or 7 positions from fluorine-containing aliphatic precursors and suitably substituted pyrimidines is described. The fluorine-containing pterins were found to be very insoluble and also stable to nucleophiles and bases in dilute aqueous solution. Copyright (C) 1996 Elsevier Science Ltd
引用
收藏
页码：13017 / 13026
页数：10
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