CYP2D6-SPECIFIC CD4+CD25+REGULATORY T-CELLS INHIBIT TH1 AND TH17, BUT PROMOTE TH2 CYTOKINE SECRETION IN PATIENTS WITH AUTOIMMUNE HEPATITIS TYPE 2

被引:0
|
作者
Longhi, Maria Serena [1 ]
Hussain, Munther J. [1 ]
Mieli-Vergoni, Giorgina [1 ]
Ma, Yun [1 ]
Vergani, Diego [1 ]
机构
[1] Kings Coll London, Sch Med, Univ London Kings Coll Hosp, Inst Liver Studies, London WC2R 2LS, England
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
248
引用
收藏
页码:421A / 421A
页数:1
相关论文
共 50 条
  • [1] CYP2D6-specific CD4+CD25+ regulatory T-cells inhibit Th1 and Th17, but promote Th2 cytokine secretion in patients with autoimmune hepatitis type 2
    Longhi, M. S.
    Hussain, M. J.
    Mieli-Vergani, G.
    Ma, Y.
    Vergani, D.
    IMMUNOLOGY, 2008, 125 : 119 - 119
  • [2] Cutting Edge: CD1d Restriction and Th1/Th2/Th17 Cytokine Secretion by Human Vδ3 T Cells
    Mangan, Bozgana A.
    Dunne, Margaret R.
    O'Reilly, Vincent P.
    Dunne, Padraic J.
    Exley, Mark A.
    O'Shea, Donal
    Scotet, Emmanuel
    Hogan, Andrew E.
    Doherty, Derek G.
    JOURNAL OF IMMUNOLOGY, 2013, 191 (01): : 30 - 34
  • [3] Rapamycin ameliorates experimental autoimmune uveoretinitis by inhibiting Th1/Th2/Th17 cells and upregulating CD4+CD25+ Foxp3 regulatory T cells
    Li-Fei Yuan
    Guang-Da Li
    Xin-Jun Ren
    Hong Nian
    Xiao-Rong Li
    Xiao-Min Zhang
    International Journal of Ophthalmology, 2015, (04) : 659 - 664
  • [4] Tacrolimus and regulatory CD4+CD25+T cells inhibit Th1 and Th2 responses in individuals with atopic dermatitis
    Birch, K
    Vukmanovic-Stejic, M
    Mcquaid, A
    Reed, J
    Macgregor, C
    Akbar, A
    Rustin, M
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2005, 125 (03) : A36 - A36
  • [5] TH1, TH2, or TH17 Circuits Independently Promote Colitis in the Absence of Regulatory T Cells
    Metwali, Ahmed
    Berg, Daniel
    Vennalaganti, R. Prashanth
    Ince, M. Nedim
    Polyak, Steven
    Winckler, Sarah
    Broadhurst, Kim
    Elliott, David E.
    GASTROENTEROLOGY, 2012, 142 (05) : S863 - S863
  • [6] Expression of Th1, Th2 and Th17 cytokines in CD4+ T cells in peripheral blood of asthma patients
    Ceryis, Luminita
    Jung, Matthias
    Schiffer, Timo
    Korn, Stephanie
    Buhl, Roland
    EUROPEAN RESPIRATORY JOURNAL, 2014, 44
  • [7] TH1 AND TH2 CD4(+) T-CELLS IN THE PATHOGENESIS OF ORGAN-SPECIFIC AUTOIMMUNE-DISEASES
    LIBLAU, RS
    SINGER, SM
    MCDEVITT, HO
    IMMUNOLOGY TODAY, 1995, 16 (01): : 34 - 38
  • [8] CD4+CD25+T regulatory cells in SJL mice regulate development of Th1 and Th2 immunity
    Hussain, Shabbir
    Kirwin, Stefanie
    Stohlman, Stephen
    JOURNAL OF IMMUNOLOGY, 2010, 184
  • [9] Immunomodulation of human CD19+CD25high regulatory B cells via Th17/Foxp3 regulatory T cells and Th1/Th2 cytokines
    Hong, Min
    Liao, Yun
    Liang, Jin
    Chen, Xiao
    Li, Shaoyou
    Liu, Weiqing
    Gao, Change
    Zhong, Zhaoming
    Kong, Deyu
    Deng, Jun
    Zhang, Jie
    Pan, Guoqing
    HUMAN IMMUNOLOGY, 2019, 80 (10) : 863 - 870
  • [10] CD4+CD25+ Regulatory T Cells Suppress the Developmental Pathway From TH17 to Alternative TH1 Cells via TH17/TH1 and TH1-Like Cells
    Sujino, Tomohisa
    Kanai, Takanori
    Ono, Yuuichi
    Mikami, Yohei
    Hayashi, Atsushi
    Doi, Tomomitsu
    Matsuoka, Katsuyoshi
    Lisamatsu, Tadakazu I.
    Takaishi, Illiromasa
    Ogata, Haruhiko
    Yoshimura, Akihiko
    Hibi, Toshifumi
    GASTROENTEROLOGY, 2011, 140 (05) : S150 - S150