Steroidal saponins from the rhizome of Polygonatum sibiricum

被引：50
作者：
Tang, Cheng [1 ]
Yu, Ya-Ming [1 ]
Qi, Qing-Ling [4 ]
Wu, Xiao-Dan [1 ]
Wang, Jia [1 ]
Tang, Sheng-An [1 ,2 ,3 ]
机构：
[1] Tianjin Med Univ, Sch Pharm, Tianjin Key Lab Technol Enabling Dev Clin Therape, Tianjin 300070, Peoples R China
[2] Chinese Acad Med Sci, Inst Mat Med, State Key Lab Bioact Subst & Funct Nat Med, Beijing, Peoples R China
[3] Peking Union Med Coll, Beijing, Peoples R China
[4] Tianjin Univ Tradit Chinese Med, Affiliated Hosp 1, Dept Anesthesiol, Tianjin 300193, Peoples R China
来源：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2019年 / 21卷 / 03期
基金：
中国国家自然科学基金;
关键词：
Polygonatum sibiricum; steroidal saponins; structural elucidation; anti-inflammatory activity; GLYCOSIDES; ODORATUM;
D O I：
10.1080/10286020.2018.1478815
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Four new steroidal saponins, 3-O--D-glucopyranosyl(14)--D-fucopyranosyl -(25R)-spirost-5-en-3,17-diol (1), 3-O--D-glucopyranosyl(14)--D- fucopyranosyl-(25S)-spirost-5-en-3,17-diol (2), 3-O--D-glucopyranosyl(12) --D-glucopyranosyl(14)--D-fucopyranosyl-(25R)-spirost-5-en-3,17-diol (3), 3-O--D-glucopyranosyl(14)--D-fucopyranosyl-(25R/S)-spirost-5-en-3,12-diol (4), together with five known steroidal saponins were isolated from the ethanolic extract of the rhizome of Polygonatum sibiricum. Chemical structures of these compounds were elucidated by spectroscopic techniques. Anti-inflammatory activities of these new compounds were evaluated. [GRAPHICS] .
引用
收藏
页码：197 / 206
页数：10
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