Complete genome sequence of a potential foot-and-mouth disease virus serotype O vaccine strain from Bangladesh

被引:0
|
作者
Al Amin, Md. [1 ,2 ]
Ali, Md. Rahmat [1 ,3 ]
Alam, A. S. M. Rubayet Ul [1 ,4 ]
Siddique, Mohammad Anwar [1 ,5 ]
Rahaman, Md. Mizanur [1 ]
Sultana, Munawar [1 ]
Hossain, Md. Anwar [1 ,6 ]
机构
[1] Univ Dhaka, Dept Microbiol, Dhaka 1000, Bangladesh
[2] Dept Livestock Serv, Qual Control Lab, Dhaka, Bangladesh
[3] Minist Foreign Affairs, Dhaka, Bangladesh
[4] Jashore Univ Sci & Technol, Dept Microbiol, Jashore 7408, Bangladesh
[5] Northwestern Univ, Feinberg Sch Med, Chicago, IL 60611 USA
[6] Jashore Univ Sci & Technol, Jashore 7408, Bangladesh
关键词
PROTEIN;
D O I
10.1007/s00705-020-04711-6
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
One of the six sublineages of the dominant O/ME-SA/Ind2001 lineage of foot-and-mouth disease virus (FMDV), Ind2001BD1 has already spread throughout 14 countries, including Bangladesh. Here, we report the complete genome sequence of the potential serotype O vaccine strain BAN/TA/Dh-301/2016, which has been shown to provide protection against all the circulating serotype O viruses in Bangladesh. The viral genome is 8,211 nucleotide (nt) long with an open reading frame (ORF) of 6999 nt. The ORF is flanked by a 1098-nt-long 5 '-UTR and a 114-nt-long 3 '-UTR. Compared to the Indian FMDV serotype O vaccine strain O/India/R2/75 (AF204276), ten mutations were identified in the major antigenic sites of BAN/TA/Dh-301/2016 (MK088170.1).
引用
收藏
页码:2119 / 2122
页数:4
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