Regulatory networks controlling Candida albicans morphogenesis

被引：245

作者：

Brown, AJP ^{[1
]}

Gow, NAR ^{[1
]}

机构：

[1] Univ Aberdeen, Dept Mol & Cell Biol, Inst Med Sci, Aberdeen AB25 2ZD, Scotland

来源：

TRENDS IN MICROBIOLOGY | 1999年 / 7卷 / 08期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/S0966-842X(99)01556-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Candida albicans undergoes reversible morphogenetic transitions between budding, pseudohyphal and hyphal growth forms that promote the virulence of this pathogenic fungus. The regulatory networks that control morphogenesis are being elucidated; however, the primary signals that trigger morphogenesis remain obscure, and the physiological outputs of these networks are complex.

引用

页码：333 / 338

页数：6

共 63 条

[1] The Candida albicans HYR1 gene, which is activated in response to hyphal development: Belongs to a gene family encoding yeast cell wall proteins [J].

Bailey, DA ;

Feldmann, PJF ;

Bovey, M ;

Gow, NAR ;

Brown, AJP .

JOURNAL OF BACTERIOLOGY, 1996, 178 (18) :5353-5360

[2] CLONING AND CHARACTERIZATION OF ECE1, A GENE EXPRESSED IN ASSOCIATION WITH CELL ELONGATION OF THE DIMORPHIC PATHOGEN CANDIDA-ALBICANS [J].

BIRSE, CE ;

IRWIN, MY ;

FONZI, WA ;

SYPHERD, PS .

INFECTION AND IMMUNITY, 1993, 61 (09) :3648-3655

[3] BINDING-SITES FOR LH IN CANDIDA-ALBICANS - COMPARISON WITH THE MAMMALIAN CORPUS-LUTEUM LH RECEPTOR [J].

BRAMLEY, TA ;

MENZIES, GS ;

WILLIAMS, RJ ;

KINSMAN, OS ;

ADAMS, DJ .

JOURNAL OF ENDOCRINOLOGY, 1991, 130 (02) :177-190

[4] Control of filament formation in Candida albicans by the transcriptional repressor TUP1 [J].

Braun, BR ;

Johnson, AD .

SCIENCE, 1997, 277 (5322) :105-109

[5] Cell wall and secreted proteins of Candida albicans:: Identification, function, and expression [J].

Chaffin, WL ;

López-Ribot, JL ;

Casanova, M ;

Gozalbo, D ;

Martinez, JP .

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 1998, 62 (01) :130-+

[6] MOLECULAR-BASIS OF CELL INTEGRITY AND MORPHOGENESIS IN SACCHAROMYCES-CEREVISIAE [J].

CID, VJ ;

DURAN, A ;

DELREY, F ;

SNYDER, MP ;

NOMBELA, C ;

SANCHEZ, M .

MICROBIOLOGICAL REVIEWS, 1995, 59 (03) :345-386

[7] Constitutive activation of the Saccharomyces cerevisiae mating response pathway by a MAP kinase kinase from Candida albicans [J].

Clark, KL ;

Feldmann, PJF ;

Dignard, D ;

Larocque, R ;

Brown, AJP ;

Lee, MG ;

Thomas, DY ;

Whiteway, M .

MOLECULAR AND GENERAL GENETICS, 1995, 249 (06) :609-621

[8] Yeast-enhanced green fluorescent protein (yEGFP): A reporter of gene expression in Candida albicans [J].

Cormack, BP ;

Bertram, G ;

Egerton, M ;

Gow, NAR ;

Falkow, S ;

Brown, AJP .

MICROBIOLOGY-UK, 1997, 143 :303-311

[9] Derepressed hyphal growth and reduced virulence in a VH1 family-related protein phosphatase mutant of the human pathogen Candida albicans [J].

Csank, C ;

Makris, C ;

Meloche, S ;

Schroppel, K ;

Rollinghoff, M ;

Dignard, D ;

Thomas, DY ;

Whiteway, M .

MOLECULAR BIOLOGY OF THE CELL, 1997, 8 (12) :2539-2551

[10]

Edgington NP, 1999, MOL CELL BIOL, V19, P1369

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