Light-Induced Modular Ligation of Conventional RAFT Polymers

被引：94

作者：

Oehlenschlaeger, Kim K. ^{[1
]}

Mueller, Jan O. ^{[1
]}

Heine, Niklas B. ^{[1
]}

Glassner, Mathias ^{[1
]}

Guimard, Nathalie K. ^{[1
]}

Delaittre, Guillaume ^{[1
]}

Schmidt, Friedrich G. ^{[2
]}

Barner-Kowollik, Christopher ^{[1
]}

机构：

[1] Karlsruhe Inst Technol, Inst Tech Chem & Polymerchem, D-76128 Karlsruhe, Germany

[2] Evon Ind AG, D-45764 Marl, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2013年 / 52卷 / 02期

关键词：

click chemistry; Diels-Alder reaction; photoenols; polymer ligation; RAFT agents; LIVING RADICAL POLYMERIZATION; FRAGMENTATION CHAIN TRANSFER; STAR BLOCK-COPOLYMERS; CLICK-CHEMISTRY; AMBIENT-TEMPERATURE; MATERIAL SCIENCE; CONJUGATION; COMBINATION; UPDATE; ATRP;

D O I：

10.1002/anie.201206905

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Making light work of RAFT conjugation: A non-activated RAFT agent at the end of RAFT polymers can readily be coupled with ortho-quinodimethanes (photoenols) in a photo-triggered Diels-Alder reaction under mild conditions without catalyst (see scheme). The method is universal and opens the door for the conjugation of a large number of RAFT-prepared polymers with photoenol-functionalized (macro)molecules. (RAFT=reversible addition- fragmentation chain transfer.) Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

引用

页码：762 / 766

页数：5

共 41 条

[1] "Clicking" Polymers or Just Efficient Linking: What Is the Difference? [J].

Barner-Kowollik, Christopher ;

Du Prez, Filip E. ;

Espeel, Pieter ;

Hawker, Craig J. ;

Junkers, Tanja ;

Schlaad, Helmut ;

Van Camp, Wim .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 50 (01) :60-62

[2] On the Quantitative Click Conjugation of Molecular Weight Distributions: What Can Theoretically Be Expected? [J].

Barner-Kowollik, Christopher .

MACROMOLECULAR RAPID COMMUNICATIONS, 2009, 30 (19) :1625-1631

[3] Has Click Chemistry Lead to a Paradigm Shift in Polymer Material Design? [J].

Barner-Kowollik, Christopher ;

Inglis, Andrew J. .

MACROMOLECULAR CHEMISTRY AND PHYSICS, 2009, 210 (12) :987-992

[4]

BarnerKowollik C., 2008, Handbook of RAFT Polymerization

[5] 'Click' chemistry in polymer and material science: An update [J].

Binder, Wolfgang H. ;

Sachsenhofer, Robert .

MACROMOLECULAR RAPID COMMUNICATIONS, 2008, 29 (12-13) :952-981

[6] Building Nanostructures Using RAFT Polymerization [J].

Boyer, Cyrille ;

Stenzel, Martina H. ;

Davis, Thomas P. .

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2011, 49 (03) :551-595

[7] Fragmentation pathways of methacrylic homopolymers with labile trialkylsilyl ester side-groups-A mass spectrometric investigation of the RAFT process [J].

Charles, Laurence ;

Lejars, Marlene ;

Margaillan, Andre ;

Bressy, Christine .

INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2012, 311 :31-39

[8] ORTHOQUINODIMETHANES [J].

CHARLTON, JL ;

ALAUDDIN, MM .

TETRAHEDRON, 1987, 43 (13) :2873-2889

[9] Photoclickable Surfaces for Profluorescent Covalent Polymer Coatings [J].

Dietrich, Mathias ;

Delaittre, Guillaume ;

Blinco, James P. ;

Inglis, Andrew J. ;

Bruns, Michael ;

Barner-Kowollik, Christopher .

ADVANCED FUNCTIONAL MATERIALS, 2012, 22 (02) :304-312

[10] (Ultra)Fast Catalyst-Free Macromolecular Conjugation in Aqueous Environment at Ambient Temperature [J].

Glassner, Mathias ;

Delaittre, Guillaume ;

Kaupp, Michael ;

Blinco, James P. ;

Barner-Kowollik, Christopher .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 134 (17) :7274-7277

← 1 2 3 4 5 →