Room temperature palladium-catalyzed intramolecular hydroamination of unactivated alkenes

被引：180

作者：

Michael, FE ^{[1
]}

Cochran, BM ^{[1
]}

机构：

[1] Univ Washington, Seattle, WA 98195 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2006年 / 128卷 / 13期

关键词：

D O I：

10.1021/ja060126h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A mild and facile Pd-catalyzed intramolecular hydroamination of unactivated alkenes is described. This reaction takes place at room temperature and is tolerant of synthetically useful acid-sensitive functional groups. The formation of hydroamination products rather than oxidative amination products is due to the use of a tridentate ligand on Pd which effectively inhibits β-hydride elimination. Copyright © 2006 American Chemical Society.

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页码：4246 / 4247

页数：2

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