A randomized, controlled trial of acupuncture self-needling as maintenance therapy for cancer-related fatigue after therapist-delivered acupuncture

被引：60

作者：

Molassiotis, A. ^{[1
,2
]}

Bardy, J. ^{[1
]}

Finnegan-John, J. ^{[3
]}

Mackereth, P. ^{[4
]}

Ryders, W. D. ^{[5
]}

Filshie, J. ^{[6
]}

Ream, E. ^{[3
]}

Eaton, D. ^{[7
]}

Richardson, A. ^{[8
]}

机构：

[1] Univ Manchester, Sch Nursing Midwifery & Social Work, Manchester M13 9PL, Lancs, England

[2] Hong Kong Polytech Univ, Sch Nursing, Hong Kong, Hong Kong, Peoples R China

[3] Kings Coll London, Florence Nightingale Sch Nursing & Midwifery, London WC2R 2LS, England

[4] Christie NHS Fdn Trust, Rehabil Unit, Manchester, Lancs, England

[5] Christie NHS Fdn Trust, Clin Trials Unit, Manchester, Lancs, England

[6] Royal Marsden Hosp NHS Fdn Trust, London, England

[7] Royal Lancaster Infirm, Lancaster, England

[8] Univ Southampton, Fac Hlth Sci, Univ Hosp Southampton NHS Fdn Trust, Southampton, Hants, England

来源：

ANNALS OF ONCOLOGY | 2013年 / 24卷 / 06期

关键词：

acupuncture; breast cancer; fatigue; maintenance treatment; self-acupuncture; self-needling;

D O I：

10.1093/annonc/mdt034

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background: Maintenance acupuncture is advocated by clinicians after successful clinic-based acupuncture. We aimed to assess the effectiveness of maintenance acupuncture in the management of cancer-related fatigue (CRF); treatment delivered by therapists or self-acupuncture/self-needling was compared with no maintenance treatment. Methods: Breast cancer patients who participated in a randomized trial of acupuncture for CRF management (reported elsewhere) were re-randomized to receive an additional four acupuncturist-delivered weekly sessions; four self-administered weekly acupuncture sessions (self-needling); or no acupuncture. Primary outcome was general fatigue (Multidimensional Fatigue Inventory). Mood, quality of life and safety were also assessed. Results: In total, 197 patients were re-randomized, with 65 to therapist-delivered sessions, 67 to self-acupuncture/self-needling and 65 to no further acupuncture. Primary outcome scores were equivalent between the therapist-delivered acupuncture and self-acupuncture (P > 0.05). A non-significant trend in improving fatigue was observed at the end of 4 weeks in the combined acupuncture arms (P = 0.07). There was no impact on mood or quality of life of the further acupuncture sessions at 18 weeks beyond the improvement observed in initial trial. Conclusion: Self-acupuncture is an acceptable, feasible and safe maintenance treatment for patients with CRF. However, overall, maintenance acupuncture did not yield important improvements beyond those observed after an initial clinic-based course of acupuncture.

引用

页码：1645 / 1652

页数：8

共 14 条

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