Luminal and Mucosal Microbiota of the Cecum and Large Colon of Healthy and Diarrheic Horses

被引：31

作者：

Arroyo, Luis G. ^{[1
]}

Rossi, Laura ^{[2
]}

Santos, Bruna P. ^{[1
]}

Gomez, Diego E. ^{[1
]}

Surette, Michael G. ^{[2
]}

Costa, Marcio C. ^{[3
]}

机构：

[1] Univ Guelph, Ontario Vet Coll, Dept Clin Studies, Guelph, ON N1G 2W1, Canada

[2] McMaster Univ, Farncombe Family Digest Hlth Res Inst, Dept Med, Hamilton, ON L8S 4L8, Canada

[3] Univ Montreal, Fac Med Vet, Dept Biomed Sci, St Hyacinthe, PQ J2S 6Z7, Canada

来源：

ANIMALS | 2020年 / 10卷 / 08期

关键词：

intestinal microbiota; equine colitis; diarrhea; BACTERIAL MICROBIOTA; COLITIS; ENTERITIS;

D O I：

10.3390/ani10081403

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Simple Summary Acute diarrhea (colitis) is a major problem in adult horses and the role of the intestinal bacteria (microbiota) is still poorly understood in this species. The aim of this study was to compare the mucosal and luminal content microbiota of the cecum and colon of healthy and diarrheic horses. We concluded that microbial dysbiosis (changes in the normal microbiota composition) occurs in horses with colitis at different levels of the intestinal tract and microbiota composition is different between the mucosa and luminal content of diarrheic horses. Changes in species associated with dysbiosis could be used in the future for disease diagnosis, prognosis and treatment of equine colitis. The aim of this study was to compare the mucosal and luminal content microbiota of the cecum and colon of healthy and diarrheic horses. Marked differences in the richness and in the community composition between the mucosal and luminal microbiota of the cecum and large colon of horses with colitis were observed. Microbial dysbiosis occurs in horses with colitis at different levels of the intestinal tract, and microbiota composition is different between the mucosa and luminal content of diarrheic horses. The changes in some key taxa associated with dysbiosis in the equine intestinal microbiota, such asEscherichia,FusobacteriumandLactobacillus, deserve further inquiry in order to determine their utility for disease diagnosis and treatment.

引用

页码：1 / 12

页数：11

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