Novel triterpenoid saponins from the seeds of Celosia argentea L.

被引：24

作者：

Wu, Qing Bin ^{[1
]}

Wang, Yan ^{[1
]}

Liang, Lin ^{[1
]}

Jiang, Qian ^{[1
]}

Guo, Mei Li ^{[1
]}

Zhang, Jun Jie ^{[2
]}

机构：

[1] Second Mil Med Univ, Sch Pharm, Dept Pharmacognosy, Shanghai 200433, Peoples R China

[2] Shanghai Changhai Hosp, Dept Obstet & Gynecol, Shanghai 200433, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2013年 / 27卷 / 15期

关键词：

amaranthaceae; Celosia argentea L; triterpenoid saponins; hepatoprotective effects; ANTIMITOTIC BICYCLIC PEPTIDES; CARBON-TETRACHLORIDE; CYCLIC PEPTIDE; HEPATOTOXICITY; MICE;

D O I：

10.1080/14786419.2012.740034

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Two new triterpenoid saponins celosin I (1) and celosin II (2) were isolated from the seeds of Celosia argentea L. (Amaranthaceae). The structures of the two new compounds were elucidated based on chemical analysis and spectral methods (IR, 1-D and 2-D NMR, ESI-MS, HR-ESI-MS). They exhibited significant hepatoprotective effect on carbon tetrachloride-induced and N,N-dimethylformamide-induced hepatotoxicity in mice.

引用

页码：1353 / 1360

页数：8

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