Purpose of review Optical coherence tomography (OCT) has revolutionized the clinical practice of ophthalmology. It is a noninvasive imaging technique that provides high-resolution, cross-sectional images of the retina, retinal nerve fiber layer and the optic nerve head. This review discusses the present applications of the commercially available spectral-domain OCT (SD-OCT) systems in the diagnosis and management of retinal diseases, with particular emphasis on choroidal imaging. Future directions of OCT technology and their potential clinical uses are discussed. Recent findings Analysis of the choroidal thickness in healthy eyes and disease states such as age-related macular degeneration, central serous chorioretinopathy, diabetic retinopathy and inherited retinal dystrophies has been successfully achieved using SD-OCT devices with software improvements. Future OCT innovations such as longer-wavelength OCT systems including the swept-source technology, along with Doppler OCT and en-face imaging, may improve the detection of subtle microstructural changes in chorioretinal diseases by improving imaging of the choroid. Summary Advances in OCT technology provide for better understanding of pathogenesis, improved monitoring of progression and assistance in quantifying response to treatment modalities in diseases of the posterior segment of the eye. Further improvements in both hardware and software technologies should further advance the clinician's ability to assess and manage chorioretinal diseases.
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Doheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Univ So Calif, Keck Sch Med, Dept Ophthalmol, Los Angeles, CA 90033 USADoheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Wang, Y.
;
Lu, A.
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Doheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Univ So Calif, Keck Sch Med, Dept Ophthalmol, Los Angeles, CA 90033 USADoheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Lu, A.
;
Gil-Flamer, J.
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机构:
Doheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Univ So Calif, Keck Sch Med, Dept Ophthalmol, Los Angeles, CA 90033 USADoheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Gil-Flamer, J.
;
Tan, O.
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机构:
Doheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Univ So Calif, Keck Sch Med, Dept Ophthalmol, Los Angeles, CA 90033 USADoheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Tan, O.
;
Izatt, J. A.
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Duke Univ, Dept Biomed Engn, Durham, NC 27706 USADoheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Izatt, J. A.
;
Huang, D.
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机构:
Doheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Univ So Calif, Keck Sch Med, Dept Ophthalmol, Los Angeles, CA 90033 USADoheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
机构:
Moorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, EnglandMoorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
Yeoh, Jonathan
;
Rahman, Waheeda
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机构:Moorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
Rahman, Waheeda
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Chen, Fred
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Moorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
UCL Inst Ophthalmol, London, EnglandMoorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
Chen, Fred
;
Hooper, Claire
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机构:Moorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
Hooper, Claire
;
Patel, Praveen
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Moorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
UCL Inst Ophthalmol, London, EnglandMoorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
Patel, Praveen
;
Tufail, Adnan
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Moorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
UCL Inst Ophthalmol, London, EnglandMoorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
Tufail, Adnan
;
Webster, Andrew R.
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Moorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
UCL Inst Ophthalmol, London, EnglandMoorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
Webster, Andrew R.
;
Moore, Anthony T.
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Moorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
UCL Inst Ophthalmol, London, EnglandMoorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
Moore, Anthony T.
;
DaCruz, Lyndon
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Moorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
UCL Inst Ophthalmol, London, EnglandMoorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
机构:
Doheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Univ So Calif, Keck Sch Med, Dept Ophthalmol, Los Angeles, CA 90033 USADoheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Wang, Y.
;
Lu, A.
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机构:
Doheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Univ So Calif, Keck Sch Med, Dept Ophthalmol, Los Angeles, CA 90033 USADoheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Lu, A.
;
Gil-Flamer, J.
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机构:
Doheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Univ So Calif, Keck Sch Med, Dept Ophthalmol, Los Angeles, CA 90033 USADoheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Gil-Flamer, J.
;
Tan, O.
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机构:
Doheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Univ So Calif, Keck Sch Med, Dept Ophthalmol, Los Angeles, CA 90033 USADoheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Tan, O.
;
Izatt, J. A.
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机构:
Duke Univ, Dept Biomed Engn, Durham, NC 27706 USADoheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Izatt, J. A.
;
Huang, D.
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机构:
Doheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
Univ So Calif, Keck Sch Med, Dept Ophthalmol, Los Angeles, CA 90033 USADoheny Eye Inst, Ctr Ophthalm Opt & Lasers, Los Angeles, CA 90033 USA
机构:
Moorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, EnglandMoorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
Yeoh, Jonathan
;
Rahman, Waheeda
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机构:Moorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
Rahman, Waheeda
;
Chen, Fred
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Moorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
UCL Inst Ophthalmol, London, EnglandMoorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
Chen, Fred
;
Hooper, Claire
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机构:Moorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
Hooper, Claire
;
Patel, Praveen
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机构:
Moorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
UCL Inst Ophthalmol, London, EnglandMoorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
Patel, Praveen
;
Tufail, Adnan
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Moorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
UCL Inst Ophthalmol, London, EnglandMoorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
Tufail, Adnan
;
Webster, Andrew R.
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机构:
Moorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
UCL Inst Ophthalmol, London, EnglandMoorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
Webster, Andrew R.
;
Moore, Anthony T.
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Moorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
UCL Inst Ophthalmol, London, EnglandMoorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
Moore, Anthony T.
;
DaCruz, Lyndon
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Moorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England
UCL Inst Ophthalmol, London, EnglandMoorfields Eye Hosp, NIHR Biomed Res Ctr Ophthalmol, London EC1V 2PD, England