Prolactinoma in some Meniere's patients - Is stress involved?

被引:18
作者
Horner, KC
Guieu, RG
Magnan, J
Chays, A
Cazals, Y
机构
[1] Hop Nord Marseille, Lab Otol, Marseille, France
[2] Hop Nord Marseille, CNRS, UMR 6560, Marseille, France
[3] Hop Nord Marseille, Serv ORL, Marseille, France
关键词
stress; vertigo; hearing; tinnitus; prolactin; dopamine;
D O I
10.1016/S0893-133X(01)00356-6
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Dizziness is a common complaint in primary care clinics and can enter the diagnostic profile of different pathologies spanning from psychiatric problems to vestibular dysfunction, Episodes of vertigo in Meniere's patients are often reported to be triggered by stress but no physiological data are available to account for the subjective link. The study involved 42 Meniere's patients hospitalized for neurectomy of the vestibular nerve for relief of incapacitating vertigo. In addition 18 patients with neurinoma of the vestibular nerve and 12 patients with facial spasm, who underwent surgery, served as controls. A blood sample was taken on the day of surgery in order to determine the level of battery of different stress hormones. The most striking observation was the presence of hyperprolactinemia (above 20 mug/l) in 14 Meniere's patients. The presence of prolactinoma was confirmed by MRI in six cases out of six investigated and the others have not yet been followed tip in this retrospective study. These observations are clearly indicative for systematic determination of prolactin levels before opting for surgery in Meniere's patients. [Neuropsychopharmacology 26:135-138,,2002] (C) 2001 American College of Neuropsychopharmacology. Published by Elsevier Science Inc.
引用
收藏
页码:135 / 138
页数:4
相关论文
共 17 条
[1]   Stress and symptoms of Meniere's disease: A time-series analysis [J].
Andersson, G ;
Hagnebo, C ;
Yardley, L .
JOURNAL OF PSYCHOSOMATIC RESEARCH, 1997, 43 (06) :595-603
[2]   Vertigo [J].
Baloh, RW .
LANCET, 1998, 352 (9143) :1841-1846
[3]  
Biller BMK, 1999, J REPROD MED, V44, P1075
[4]  
BLAGOVESHCHENSK.NS, 1988, ZH VOPR NEIROKHIR IM, V2, P24
[5]   NEUROTRANSMITTERS AND NEUROMODULATORS OF THE MAMMALIAN COCHLEA [J].
EYBALIN, M .
PHYSIOLOGICAL REVIEWS, 1993, 73 (02) :309-373
[6]   PSYCHOSOMATIC ASPECTS OF MENIERES DISEASE [J].
FOWLER, EP ;
ZECKEL, A .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1952, 148 (15) :1265-1268
[7]   Prolactin: structure, function, and regulation of secretion [J].
Freeman, ME ;
Kanyicska, B ;
Lerant, A ;
Nagy, G .
PHYSIOLOGICAL REVIEWS, 2000, 80 (04) :1523-1631
[8]   Evaluating dizziness [J].
Hoffman, RM ;
Einstadter, D ;
Kroenke, K .
AMERICAN JOURNAL OF MEDICINE, 1999, 107 (05) :468-478
[9]   Sympathectomy improves the ear's resistance to acoustic trauma - could stress render the ear more sensitive? [J].
Horner, KC ;
Giraudet, F ;
Lucciano, M ;
Cazals, Y .
EUROPEAN JOURNAL OF NEUROSCIENCE, 2001, 13 (02) :405-408
[10]   COMMITTEE ON HEARING AND EQUILIBRIUM GUIDELINES FOR THE DIAGNOSIS AND EVALUATION OF THERAPY IN MENIERES-DISEASE [J].
MONSELL, EM ;
BALKANY, TA ;
GATES, GA ;
GOLDENBERG, RA ;
MEYERHOFF, WL ;
HOUSE, JW .
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 1995, 113 (03) :181-185