Cancer Precision Medicine: From Cancer Screening to Drug Selection and Personalized Immunotherapy

被引：58

作者：

Deng, Xiaolan ^{[1
]}

Nakamura, Yusuke ^{[1
]}

机构：

[1] Univ Chicago, Dept Med, Sect Hematol Oncol, 5841 S Maryland Ave,MC2115, Chicago, IL 60637 USA

来源：

TRENDS IN PHARMACOLOGICAL SCIENCES | 2017年 / 38卷 / 01期

关键词：

CIRCULATING TUMOR-CELLS; II CLINICAL-TRIAL; T-CELLS; LUNG-CANCER; COLORECTAL-CANCER; PHASE-II; KRAS MUTATIONS; CHEMOTHERAPY; PEPTIDES; DNA;

D O I：

10.1016/j.tips.2016.10.013

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

With the accelerating progress in basic and clinical cancer research, a huge body of new discoveries and powerful technologies has allowed us to implement a 'Cancer Precision Medicine (CPM)' system for cancer patients. The CPM system covers a wide range of cancer management including cancer screening, monitoring of relapse/recurrence, selection/prediction of effective drugs/treatments, and personalized immunotherapy. In this system individual cancer patients expect to receive personalized care: an appropriate dose of the right drug at the right time. We here aim to summarize and discuss a possible workflow for precision medicine for cancer patients by reviewing recent booming technologies and treatments that have been used or will potentially be used in the CPM system.

引用

页码：15 / 24

页数：10

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