Proteins and cyanine dyes. Part III. Synthesis and spectroscopic studies of benzothiazolo-4[1,2,6-trimethylpyridinium] monomethine cyanine dyes for fluorescent detection of bovine serum albumin in solutions

被引：38

作者：

Yarmoluk, SM ^{[1
]}

Kryvorotenko, DV ^{[1
]}

Balanda, AO ^{[1
]}

Losytskyy, MY ^{[1
]}

Kovalska, VB ^{[1
]}

机构：

[1] Natl Acad Sci Ukraine, Inst Mol Biol & Genet, UA-03143 Kiev, Ukraine

来源：

DYES AND PIGMENTS | 2001年 / 51卷 / 01期

关键词：

cyanine dyes; fluorescent probes; protein detection; homogeneous assay;

D O I：

10.1016/S0143-7208(01)00055-9

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The spectral-luminescent properties of a series of new cyanine dyes as possible probes for homogeneous assay of proteins have been studied. The fluorescent cyanine dyes development was based on the principle of "affinity-modifying group" with the use of benzothiazolo-4-[1,2,6-trimethylpyridinium] monomethine as template. It was shown that the cyanine dye P-5 can be used as a sensitive and specific fluorescent probe for the detection of BSA. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：41 / 49

页数：9

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