Human recombinant activated protein C in meningococcal sepsis

被引:14
作者
Weisel, G [1 ]
Joyce, D [1 ]
Gudmundsdottir, A [1 ]
Shasby, DM [1 ]
机构
[1] Univ Iowa, Coll Med, Dept Med, Iowa City, IA 52242 USA
关键词
human recombinant activated protein C; purpura fulminans; renal failure; respiratory failure; septic shock;
D O I
10.1378/chest.121.1.292
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
A 19-year-old woman presented with purpura fulminans and septic shock; subsequently, progressive coagulopathy, widespread purpura fulminans associated with meningococcemia, severe shock, respiratory, and renal failure developed. This clinical course was associated with depletion of functional protein C levels to < 5%. We describe her clinical course and therapy with human recombinant activated protein C.
引用
收藏
页码:292 / 295
页数:4
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