Enantioselective borane reduction of aromatic ketones using chiral BINOL derivatives as ligands in an aluminum catalyst

被引：26

作者：

Lin, YM ^{[1
]}

Fu, IP ^{[1
]}

Uang, BJ ^{[1
]}

机构：

[1] Natl Tsing Hua Univ, Dept Chem, Hsinchu 300, Taiwan

来源：

TETRAHEDRON-ASYMMETRY | 2001年 / 12卷 / 23期

关键词：

D O I：

10.1016/S0957-4166(02)00008-3

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Chiral aluminum complex-catalyzed asymmetric borane reduction of aromatic ketones has been successfully carried out in the presence of (R)-BINOL derivatives as ligands. Secondary alcohols were obtained in high yields with good enantioselectivities (up to 90% e.e.). (C) 2002 Elsevier Science Ltd. All rights reserved.

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页码：3217 / 3221

页数：5

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