Synthesis and characterization of star-shaped PLLA-PEO block copolymers with temperature-sensitive sol-gel transition behavior

被引：71
作者：
Park, SY
Han, DK
Kim, SC [1 ]
机构：
[1] Korea Adv Inst Sci & Technol, Ctr Adv Funct Polymers, Taejon 305701, South Korea
[2] Korea Inst Sci & Technol, Biomat Res Ctr, Seoul 130650, South Korea
来源：
MACROMOLECULES | 2001年 / 34卷 / 26期
关键词：
D O I：
10.1021/ma010789d
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
Biodegradable, nontoxic, and temperature-sensitive star-shaped PLLA-PEO amphiphilic block copolymers were synthesized. These copolymers showed sol-gel transition behavior over the CGC with varying temperature. The location and slope of boundary curve were highly affected by the molecular weight of PLLA while conventional triblock PEO-PLLA-PEO was not. These materials have possibility to be used as injectable drug delivery system for long-term delivery of bioactive agents.
引用
收藏
页码：8821 / 8824
页数：4
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