Serum levels of immunoglobulins in children with recurrent otitis media

Seventy-seven children with recurrent otitis media took part in the study at the Department of Otorhinolaryngology and Pediatrics of the University of Sao Paulo from February 1992 to March 1995. They were administered serum immunoglobulins and the relationship between recurrent otitis media and immunodeficiency was evaluated. No total IgG and IgM values were detected below the normal level: however, seven children with low levels of subclasses of IgG were detected and a below normal IgA value was detected in a child.