Symptoms before and after Posterior Fossa Surgery in Pediatric Patients

被引：13
作者：
Turkel, Susan Beckwitt [1 ,3 ]
Krieger, Mark D. [2 ]
O'Neil, Sharon [3 ]
Jubran, Rima [3 ]
Tavare, C. Jane [3 ]
机构：
[1] Univ So Calif, Childrens Hosp Los Angeles, Keck Sch Med, Dept Psychiat, Los Angeles, CA 90027 USA
[2] Univ So Calif, Childrens Hosp Los Angeles, Keck Sch Med, Dept Neurosurg, Los Angeles, CA 90027 USA
[3] Univ So Calif, Childrens Hosp Los Angeles, Keck Sch Med, Dept Pediat, Los Angeles, CA 90027 USA
来源：
PEDIATRIC NEUROSURGERY | 2012年 / 48卷 / 01期
关键词：
Posterior fossa syndrome; Cerebellar tumors; Postoperative symptoms; CEREBELLAR MUTISM SYNDROME; TUMOR RESECTION; RISK-FACTORS; CHILDREN; LESIONS; MEDULLOBLASTOMA; COGNITION; SEQUELAE; DEFICITS; ORIGIN;
D O I：
10.1159/000337730
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The posterior fossa syndrome (PFS) is common after cerebellar tumor resection in pediatric patients. It is characterized by postoperative mutism and ataxia and associated with persistent abnormalities in mood and cognition. Method: A 2-year prospective study of children and adolescents with cerebellar tumors identified by neuroimaging was performed at the Children's Hospital Los Angeles. Results: There were 8 girls and 14 boys in the study, aged 14 months to 17 years. The tumor sizes ranged from 2 to 6.5 cm in diameter. The patients presented with ataxia, headache, vomiting, depressed or irritable mood and inattention. Symptoms of PFS were present postoperatively in all except for the 2 patients with lateral tumors. The symptoms began before resection, were most prominent immediately after surgery, and improved over time. Neuropsychological assessment of 10 patients documented a persistent cognitive decrement. Conclusion: This small, descriptive study provides information on the natural history of pediatric posterior fossa tumors from before surgery through the postoperative period. Copyright (c) 2012 S. Karger AG, Basel
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页码：21 / 25
页数：5
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