Magnetic carriers of iron nanoparticles coated with a functional polymer for high throughput bioscreening

被引：19

作者：

Maeda, M.

Kuroda, C. S.

Shimura, T.

Tada, M.

Abe, M.

Yamamuro, S.

Sumiyama, K.

Handa, H.

机构：

[1] Tokyo Inst Technol, Meguro Ku, Tokyo 1528552, Japan

[2] Nagoya Inst Technol, Showa Ku, Nagoya, Aichi 4668555, Japan

[3] Tokyo Inst Technol, Midori Ku, Yokohama, Kanagawa 2268503, Japan

来源：

JOURNAL OF APPLIED PHYSICS | 2006年 / 99卷 / 08期

关键词：

D O I：

10.1063/1.2165127

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

We synthesized iron nanoparticles, 15-20 nm in size, having saturation magnetization, M-s, of 170 emu/g. They were embedded in copolymer beads of styrene (St) and glycidyl methacrylate (GMA), which were coated with poly-GMA by seed polymerization. The resultant Fe/St-GMA/GMA beads had diameters of 100-200 nm and M-s of 60 emu/g. By coating with poly-GMA, the zeta potential of the beads changed from -93.7 to -54.8 mV, as measured by an electrophoresis method. This facilitated (as revealed by gel electrophoresis method) nonspecific protein adsorption suppression, a requisite for nanoparticles to be applied to carriers for bioscreening. (C) 2006 American Institute of Physics.

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页数：3

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