Comparison of bovine- and recombinant human-derived hyaluronidase with regard to fertilization rates and embryo morphology in a sibling oocyte model: a prospective, blinded, randomized study

被引：15

作者：

Taylor, Tyl H. ^{[1
]}

Elliott, Thomas ^{[1
]}

Colturato, Luiz F. ^{[1
]}

Straub, Robert J. ^{[1
]}

Mitchell-Leef, Dorothy ^{[1
]}

Nagy, Zsolt P. ^{[1
]}

机构：

[1] Reprod Biol Associates, Atlanta, GA 30342 USA

来源：

FERTILITY AND STERILITY | 2006年 / 85卷 / 05期

关键词：

D O I：

10.1016/j.fertnstert.2005.10.053

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The objective of the present study was to compare a traditionally used bovine-derived hyaluronidase (Hyase) with the newly developed recombinant human-derived enzyme product (Cumulase) in intracytoplasmic sperm injection (ICSI) procedures using a sibling oocyte model in a prospective randomized design. The results of the Study demonstrate that Cumulase is safe and effective in an ICSI treatment program and can provide comparable if not improved parameters, including fertilization and embryo developmental rates.

引用

页码：1544 / 1546

页数：3

共 7 条

[1] Sperm deposition site during ICSI affects fertilization and development [J].