Monitoring size and shape during cooling crystallization of ascorbic acid

被引：15

作者：

Eggers, Jan ^{[1
]}

Kempkes, Michel ^{[1
]}

Cornel, Jeroen ^{[1
]}

Mazzotti, Marco ^{[1
]}

Koschinski, Ingo ^{[2
]}

Verdurand, Elodie ^{[2
]}

机构：

[1] ETH, Inst Proc Engn, CH-8092 Zurich, Switzerland

[2] DSM Nutr Prod AG, CH-4334 Sisseln, Switzerland

来源：

CHEMICAL ENGINEERING SCIENCE | 2009年 / 64卷 / 01期

关键词：

Crystallization; Imaging; Morphology; Monitoring; Optimization; Particulate processes; INDUSTRIAL BATCH CRYSTALLIZATION; POPULATION BALANCE-EQUATIONS; ORGANIC PRODUCT; PART; SIMULATION; EVOLUTION;

D O I：

10.1016/j.ces.2008.09.025

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

Seeded batch crystallization of ascorbic acid from water is Studied. For that experiments with different linear cooling rates are carried out. The concentration is monitored in-situ with ATR-FTIR spectroscopy. Samples taken during the process were characterized using a previously presented method [Eggers. J., Kempkes. M., Mazzotti, M., 2008. Measurement of size and shape distributions of particles through image analysis. Chemical Engineering Science, in press, doi:10.1016/j.ces.2008.08.007]. It is thus possible to determine the 2D particle size distributions (PSDs) of the samples, i.e. a complete description of size and shape of the particles in the sample. Thus, the influence of operating conditions on product properties such as crystal shape is studied. (c) 2008 Elsevier Ltd. All rights reserved.

引用

页码：163 / 171

页数：9

共 16 条

[1] SOLUBILITY OF ASCORBIC, 2-FURANCARBOXYLIC, GLUTARIC, PIMELIC, SALICYCLIC, AND O-PHTHALIC ACIDS IN WATER FROM 279.15-K TO 342.15-K, AND APPARENT MOLAR VOLUMES OF ASCORBIC, GLUTARIC, AMD PIMELIC ACIDS IN WATER AT 298.15-K [J].