Modulation of thermal somatosensory thresholds within local and remote spinal dermatomes following cervical repetitive magnetic stimulation

被引：10

作者：

Albu, Sergiu ^{[1
]}

Gomez-Soriano, Julio ^{[1
,2
]}

Bravo-Esteban, Elisabeth ^{[3
]}

Palazon, Ramiro ^{[1
]}

Kumru, Hatice ^{[4
]}

Avila-Martin, Gerardo ^{[1
]}

Galan-Arriero, Iriana ^{[1
]}

Taylor, Julian ^{[1
]}

机构：

[1] Hosp Nacl Paraplej SESCAM, Sensorimotor Funct Grp, Finca La Peraleda 45071, Toledo, Spain

[2] Univ Castilla La Mancha, Escuela Enfermeria & Fisioterapia Toledo, Toledo 45070, Spain

[3] CSIC, Inst Automat Ind, Bioengn Grp, Arganda De Rey 28500, Spain

[4] Inst Guttmann Hosp Neurorehabilitacio, Barcelona 08916, Spain

来源：

NEUROSCIENCE LETTERS | 2013年 / 555卷

关键词：

Non-invasive repetitive magnetic stimulation; Thermal detection threshold; Thermal pain threshold; Contact heat evoked potentials; Dermatome; Remote neuromodulation; CORD-INJURY; PAIN; INHIBITION; EXCITABILITY; MECHANISMS; DEPRESSION; NEUROLOGY; HUMANS; RTMS;

D O I：

10.1016/j.neulet.2013.06.067

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Background: Repetitive magnetic stimulation (rMS) modulates thermal somatosensory function at both low (0.2-1.0 Hz) and high (5.0-20.0 Hz) frequencies within the conditioned dermatome. However the effects of 1 Hz and 20 Hz cervical (C6-C7) rMS on thermosensory thresholds and contact heat evoked potentials (CHEPs) tested within local and remote spinal dermatomes are not known. Methods: Thirty healthy subjects participated in the study. Warm and cold detection threshold, heat and cold pain thresholds, and Cz/Fz CHEPs were evaluated within the C6, T10 and extrasegmental V3 control dermatome, before and after random assignment of subjects to sham, 1 or 20 Hz C6-C7 rMS. Results: Following both 1 and 20 Hz cervical rMS, warm detection threshold increased within the local C6 dermatome. Furthermore 1 Hz cervical rMS increased warm detection threshold within the remote T10 dermatome, but not within the V3-trigeminal control area. Cervical rMS failed to modulate cold detection threshold, heat and cold pain threshold or Cz/Fz CHEF amplitude from the dermatomal test sites. Conclusion: Both 1 and 20 Hz cervical rMS modulated warm detection threshold within the locally conditioned C6 dermatome. The concomitant increase in warm detection threshold within the T10 dermatome following 1 Hz rMS provides evidence for remote neuromodulation of thermosensory function via intraspinal control mechanisms. (C) 2013 Elsevier Ireland Ltd. All rights reserved.

引用

页码：237 / 242

页数：6

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