Neurocognitive functions and health-related quality of life in glioblastoma patients: a concise review of the literature

被引：48
作者：
Bergo, E. [1 ]
Lombardi, G. [1 ]
Guglieri, I. [2 ]
Capovilla, E. [2 ]
Pambuku, A. [1 ]
Zagone, V. [1 ]
机构：
[1] Veneto Inst Oncol IOV IRCCS, Med Oncol Unit 1, Dept Clin & Expt Oncol, Padua, Italy
[2] Veneto Inst Oncol IOV IRCCS, Psychooncol Unit, Padua, Italy
来源：
EUROPEAN JOURNAL OF CANCER CARE | 2019年 / 28卷 / 01期
关键词：
glioma; neurocognitive functions; quality of life; LOW-GRADE GLIOMAS; RADIOTHERAPY PLUS CONCOMITANT; RANDOMIZED PHASE-III; BRAIN-TUMOR PATIENTS; LONG-TERM SURVIVORS; ADJUVANT TEMOZOLOMIDE; COGNITIVE FUNCTION; ELDERLY-PATIENTS; RADIATION-THERAPY; OLDER PATIENTS;
D O I：
10.1111/ecc.12410
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The maintenance of quality of life in patients with high-grade glioma is an important endpoint during treatment, particularly in those with glioblastoma multiforme, given its dismal prognosis; thus, the primary aims of treatments are to reduce morbidity, restore or preserve neurological functions, and the capacity to perform daily activities. This review aims to summarise what is currently known about neurocognitive outcome and quality of life in patients with high-grade glioma, particularly in glioblastoma patients. We considered all the variables that can influence neurocognitive functions, the perception of quality of life and their role as predictors for treatment outcomes.
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页数：13
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