Very often, after a fix orthodontic treatment, when the doctor removes the brackets, he notices the occurrence of white chalky spots on the facial surface of teeth and around the orthodontic rings. The purpose of this study was to monitor the evolution of the white spots lesion (WSL) arising during fixed orthodontic treatment, during a period of 6 months. After debonding, 60 selected patients were randomly divided in 3 equal groups and received different therapeutic conduct, as follows: Group nr. 1 n=20 received topical fluor applications with Profluorid Varnish; Group 2 n=20 did not receive any special treatment, but was instructed upon the correct dental brushing which must be done 2 times per day. For group no. 1 and 2, the WSL were measured with DD (DiagnoDent pen) immediately after take-off (L0), at 3 months (L3) and after 6 months (L6). Group 3 n=20 received treatment by infiltration, and the DD measurements were performed immediately after take-off (L0). The shape and size of WSL were also recorded on patient files. DD readings were subject to statistical analysis and compared between groups at the time point L0, L3 and L6 and between groups at each time point using repeated measures one-way ANOVA (alpha=0.05). Data were processed by the statistical software SPSS (ver. 13.0). The mean conclusion of this study is that Icon DMG is the most effective in restoring the damaged enamel structure in one single meeting/sitting, the aesthetic appearance being clearly superior towards the other adopted alternatives.