Iron oxide nanoparticles with sizes, shapes and compositions resulting in different magnetization signatures as potential labels for multiparametric detection

被引：102

作者：

de Montferrand, Caroline ^{[1
,2
]}

Hu, Ling ^{[3
]}

Milosevic, Irena ^{[1
]}

Russier, Vincent ^{[4
]}

Bonnin, Dominique ^{[5
]}

Motte, Laurence ^{[1
]}

Brioude, Arnaud ^{[3
]}

Lalatonne, Yoann ^{[1
,6
]}

机构：

[1] Univ Paris 13, Lab CSPBAT, CNRS, UMR 7244, F-93017 Bobigny, France

[2] Magnisense, F-75008 Paris, France

[3] Univ Lyon 1, Lab Multimat & Interfaces, CNRS, UMR 5615, F-69622 Villeurbanne, France

[4] CNRS, ICMPE, MCMC, F-94320 Thiais, France

[5] UPMC, ESPCI ParisTech, LPEM, CNRS,UMR 8213, F-75005 Paris, France

[6] Hosp Avicenne, APHP, Serv Med Nucl, F-93009 Bobigny, France

来源：

ACTA BIOMATERIALIA | 2013年 / 9卷 / 04期

关键词：

Nanoparticles; Biosensors; Superparamagnetism; Magnetic properties; Ligand exchange; SURFACE; FUNCTIONALIZATION; BISPHOSPHONATE; AKAGANEITE; DOPAMINE; BEHAVIOR; PLATFORM; UNIFORM; ANCHOR; SHELL;

D O I：

10.1016/j.actbio.2012.11.025

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

Magnetic iron oxide nanoparticles differing in their size, shape (spherical, hexagonal, rods, cubes) and composition have been synthesized and modified using caffeic acid for transfer to aqueous media and stabilization of the particle suspensions at physiological pH. A super quantum interference device and the recently patented magnetic sensor MIAplex (R), which registered a signal proportional to the second derivative of the magnetization curve, were used to study the magnetization behavior of the nanopartides. The differences in the magnetic signatures of the nanoparticles (spheres and rods) make them promising candidates for the simultaneous detection of different types of biological molecules. (C) 2012 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

引用

页码：6150 / 6157

页数：8

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