Synthesis, reactivity and biological activity of novel bisbenzofuran-2-yl-methanone derivatives

被引:25
|
作者
Kirilmis, C
Koca, M
Çukurovali, A
Ahmedzade, M
Kazaz, C
机构
[1] Univ Florence, Fac Arts & Sci, Dept Chem, TR-23119 Elazig, Turkey
[2] Ataturk Univ, Fac Arts & Sci, Dept Chem, TR-25240 Erzurum, Turkey
来源
MOLECULES | 2005年 / 10卷 / 11期
关键词
bisbenzofuran; (thio)semicarbazone; oxime; oxime ethers dervatives;
D O I
10.3390/10111399
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Preparation of bisbenzofuran-2-yl-methanone (1), the corresponding ketoxime 4, semicarbazone and thiosemicarbazone 3a and 3b, ether derivatives of the ketoximes 5a-j and the alcohol 2 are described. These substances have been prepared in excellent yields. All the synthesized compounds except 5i have been tested against five different microorganisms and some of them were found to be active against some of the species studied.
引用
收藏
页码:1399 / 1408
页数:10
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