Synthesis, reactivity and biological activity of novel bisbenzofuran-2-yl-methanone derivatives

被引：25
|
作者：
Kirilmis, C
Koca, M
Çukurovali, A
Ahmedzade, M
Kazaz, C
机构：
[1] Univ Florence, Fac Arts & Sci, Dept Chem, TR-23119 Elazig, Turkey
[2] Ataturk Univ, Fac Arts & Sci, Dept Chem, TR-25240 Erzurum, Turkey
来源：
MOLECULES | 2005年 / 10卷 / 11期
关键词：
bisbenzofuran; (thio)semicarbazone; oxime; oxime ethers dervatives;
D O I：
10.3390/10111399
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Preparation of bisbenzofuran-2-yl-methanone (1), the corresponding ketoxime 4, semicarbazone and thiosemicarbazone 3a and 3b, ether derivatives of the ketoximes 5a-j and the alcohol 2 are described. These substances have been prepared in excellent yields. All the synthesized compounds except 5i have been tested against five different microorganisms and some of them were found to be active against some of the species studied.
引用
收藏
页码：1399 / 1408
页数：10
相关论文
共 50 条
  • [1] Synthesis and Biological Activity of (2-Substituted-4-methylthiazol-5-yl) (4-substituted piperazin-1-yl) methanone Derivatives
    Mhaske, Pravin C.
    Shelke, Shivaji H.
    Raundal, Hemant N.
    Jadhav, Rahul P.
    JOURNAL OF THE KOREAN CHEMICAL SOCIETY-DAEHAN HWAHAK HOE JEE, 2014, 58 (01): : 62 - 67
  • [2] Synthesis of (2-Aminopyrimidin-4-yl)(pyridin-4-yl)methanone and Derivatives
    Giraud, Francis
    Josselin, Beatrice
    Ruchaud, Sandrine
    Anizon, Fabrice
    Moreau, Pascale
    SYNTHESIS-STUTTGART, 2023, 55 (22): : 3825 - 3832
  • [3] Synthesis and Antimicrobial Activity of Dinaphtho[2,1-b]furan-2-yl-methanone and Their Oxime Derivatives
    Kirilmis, Cumhur
    Koca, Murat
    Servi, Sueleyman
    Gur, Seher
    TURKISH JOURNAL OF CHEMISTRY, 2009, 33 (03) : 375 - 384
  • [4] Synthesis and In Vitro Protein Tyrosine Kinase Inhibitory Activity of Furan-2-yl(phenyl)methanone Derivatives
    Zheng, Fei Lang
    Ban, Shu Rong
    Feng, Xiu E.
    Zhao, Cheng Xiao
    Lin, Wenhan
    Li, Qing Shan
    MOLECULES, 2011, 16 (06): : 4897 - 4911
  • [5] Synthesis and biological activity of new bisbenzofuran-imidazolium salts
    Wang, Xue-Quan
    Ye, Ping-Ting
    Bai, Meng-Jiao
    Miu, Wei-Hang
    Yang, Zhi-Xin
    Duan, Su-Yue
    Li, Tian-Tian
    Li, Yan
    Yang, Xiao-Dong
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 30 (13)
  • [6] SYNTHESIS, REACTIVITY AND BIOLOGICAL ACTIVITY OF QUINOXALIN-2-ONE DERIVATIVES
    Ramli, Y.
    Benzeid, H.
    Bouhfid, R.
    Rodi, Y. Kandri
    Ferfra, S.
    Essassi, E. M.
    SCIENTIFIC STUDY AND RESEARCH-CHEMISTRY AND CHEMICAL ENGINEERING BIOTECHNOLOGY FOOD INDUSTRY, 2010, 11 (01): : 67 - 90
  • [7] SYNTHESIS AND ANALGESIC ACTIVITY OF (2,3-DIPHENYL-1H-INDOL-5-YL)PIPERAZIN-1-YL METHANONE DERIVATIVES
    El-Nezhawy, A. O. H.
    El-Naem, S. I.
    Galal, S. A.
    El-Diwani, H. I.
    Salam, O. M. E. Abdel
    Baiomy, A. R.
    PHARMACEUTICAL CHEMISTRY JOURNAL, 2009, 43 (01) : 25 - 29
  • [8] Synthesis and analgesic activity of (2,3-diphenyl-1H-indol-5-YL)piperazin-1-yl methanone derivatives
    A. O. H. El-Nezhawy
    S. I. El-Naem
    S. A. Galal
    H. I. El-Diwani
    O. M. E. Abdel Salam
    A. R. Baiomy
    Pharmaceutical Chemistry Journal, 2009, 43 : 25 - 29
  • [9] Synthesis, reactivity and biological activity of N(4)-boronated derivatives of 2′-deoxycytidine
    Niziol, Joanna
    Zielinski, Zbigniew
    Les, Andrzej
    Dabrowska, Magdalena
    Rode, Wojciech
    Ruman, Tomasz
    BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 22 (15) : 3906 - 3912
  • [10] Synthesis, Characterization, and in vitro Anti-Inflammatory Activity of Novel Ferrocenyl(Piperazine-1-Yl)Methanone-based Derivatives
    Ruan, Banfeng
    Li, Jin
    Guo, Qinglei
    Zhang, Min
    Pei, Zhouyang
    Hu, Yong
    MEDICINAL CHEMISTRY, 2023, 19 (09) : 915 - 924
12345