Association of the BDNF Val66Met variation with obesity in women

被引：57

作者：

Beckers, Sigri ^{[1
,2
]}

Peeters, Armand ^{[1
,2
]}

Zegers, Doreen ^{[1
,2
]}

Mertens, Ilse ^{[3
]}

Van Gaal, Luc ^{[3
]}

Van Hul, Wim ^{[1
,2
]}

机构：

[1] Univ Antwerp, Dept Med Genet, B-2610 Antwerp, Belgium

[2] Univ Antwerp Hosp, B-2610 Antwerp, Belgium

[3] Univ Antwerp Hosp, Dept Endocrinol Diabetol & Metab, B-2650 Edegem, Belgium

来源：

MOLECULAR GENETICS AND METABOLISM | 2008年 / 95卷 / 1-2期

关键词：

brain-derived neurotrophic factor; obesity; association; women; polymorphism;

D O I：

10.1016/j.ymgme.2008.06.008

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Brain-derived neurotrophic factor (BDNF) has been implied in the regulation of food intake. In the present study, we genotyped the Val66Met polymorphism in a Belgian cohort of 532 obese women and 197 healthy female controls and were, for the first time, able to show an association of the 66Met allele with obesity, at least in our female cohort. (C) 2008 Elsevier Inc. All rights reserved.

引用

收藏

页码：110 / 112

页数：3

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