The Small Membrane Filter Method of Microscopy to Diagnose Pulmonary Tuberculosis

被引：21

作者：

Fennelly, Kevin P. ^{[1
]}

Morais, Carlos Gustavo ^{[2
]}

Hadad, David Jamil ^{[2
]}

Vinhas, Solange ^{[2
]}

Dietze, Reynaldo ^{[2
]}

Palaci, Moises ^{[2
]}

机构：

[1] Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Med, Ctr Emerging Pathogens, Newark, NJ 07103 USA

[2] Univ Fed Espirito Santo, Nucleo Doencas Infecciosas, Vitoria, ES, Brazil

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2012年 / 50卷 / 06期

关键词：

D O I：

10.1128/JCM.00572-12

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We modified microscopy for acid-fast bacilli to diagnose tuberculosis (TB) using small membrane filters (SMFs) after special processing and prefiltration. With the first specimen obtained from each of 335 persons suspected of having TB, the sensitivity of the new SMF method using fluorescence microscopy (FM) was 89% (95% confidence interval [CI]: 80%, 95%). This was significantly better (P = 0.0001) than the sensitivity of routine FM of centrifuged specimens of 60% (95% CI: 49%, 71%) or that of direct sputum smears of 56% (95% CI: 40%, 72%).

引用

页码：2096 / 2099

页数：4

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